SCHEMBL1546430

SCHEMBL1546430

O=[C][C@H]1NC(=O)CCC1=O

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11503441 0.86 CRBN (0.39) CRBN
SCHEMBL7433419 0.69 HTR2A (0.42)
SCHEMBL5963193 0.68
SCHEMBL21473 0.63
SCHEMBL2267145 0.63
SCHEMBL37624 0.63
SCHEMBL737201 0.60 ITGB3 (0.34) CRBN
SCHEMBL12308060 0.60 CRBN (0.32) CRBN
SCHEMBL6271848 0.60
SCHEMBL3944202 0.60 CRBN (0.32) CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1465670-A2 LABELING TARGETING AGENTS WITH GALLIUM-68 AND GALLIUM-67 Immunomedics, Inc. (US) 2004-10-13 EP claimed
EP-1444267-A2 AFFINITY ENHANCEMENT AGENTS Immunomedics, Inc. (US) 2004-08-11 EP claimed
WO-2003059397-A2 LABELING TARGETING AGENTS WITH GALLIUM-68 AND GALLIUM-67 IMMUNOMEDICS, INC. (US) 2003-07-24 WO claimed
WO-2003033653-A2 AFFINITY ENHANCEMENT AGENTS IMMUNOMEDICS, INC. (US) 2003-04-24 WO claimed
WO-1989004672-A1 DERIVATIVES OF LINCOSAMINIDE ANTIBIOTICS THE UPJOHN COMPANY (US) 1989-06-01 WO claimed
EP-2311500-B1 Labeling targeting agents with gallium-68 and gallium-67 IMMUNOMEDICS INC (US) 2015-02-25 EP disclosed
EP-2662087-A1 Somatostatin vectors IPSEN PHARMA (FR) 2013-11-13 EP disclosed
EP-2311500-A1 Labeling targeting agents with gallium-68 and gallium-67 Immunomedics, Inc. (US) 2011-04-20 EP disclosed
EP-2161037-A2 Camptothecin-Somatostatin conjugates IPSEN PHARMA (FR) 2010-03-10 EP disclosed
EP-1624884-A4 SOMATOSTATIN VECTORS IPSEN PHARMA (FR) 2009-08-05 EP disclosed
EP-1624884-A2 SOMATOSTATIN VECTORS SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES S.A.S. (FR) 2006-02-15 EP disclosed
EP-1468097-A4 METHODS OF GENERATING MULTISPECIFIC, MULTIVALENT AGENTS FROM V sb H /sb AND V sb L /sb DOMAINS IMMUNOMEDICS INC (US) 2006-01-11 EP disclosed
WO-2004093807-A2 SOMATOSTATIN VECTORS SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES S.A.S. (FR) 2004-11-04 WO disclosed
EP-1468097-A2 METHODS OF GENERATING MULTISPECIFIC, MULTIVALENT AGENTS FROM V sb H /sb AND V sb L /sb DOMAINS Immunomedics Inc. (US) 2004-10-20 EP disclosed
EP-1444267-A2 AFFINITY ENHANCEMENT AGENTS Immunomedics, Inc. (US) 2004-08-11 EP disclosed
WO-2003057829-A2 METHODS OF GENERATING MULTISPECIFIC, MULTIVALENT AGENTS FROM VH AND VL DOMAINS IMMUNOMEDICS, INC. (US) 2003-07-17 WO disclosed
WO-2003033653-A2 AFFINITY ENHANCEMENT AGENTS IMMUNOMEDICS, INC. (US) 2003-04-24 WO disclosed
WO-1989004672-A1 DERIVATIVES OF LINCOSAMINIDE ANTIBIOTICS THE UPJOHN COMPANY (US) 1989-06-01 WO disclosed