Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | DPYD | Q12882 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | THPO | P40225 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HBB | P68871 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27917874 | 0.85 | GAA (0.40) | GAAMAPTALDH1A1LMNADPYD | |
| SCHEMBL103606 | 0.77 | GAA (0.45) | GAAMAPTALDH1A1LMNADPYD | |
| SCHEMBL27500671 | 0.75 | ALDH1A1 (0.44) | GAAMAPTALDH1A1LMNADPYD | |
| SCHEMBL28699194 | 0.75 | GAA (0.44) | GAAMAPTALDH1A1LMNADPYD | |
| SCHEMBL16893950 | 0.73 | GAA (0.54) | GAAMAPTALDH1A1LMNADPYD | |
| SCHEMBL109259 | 0.71 | GAA (0.40) | GAAMAPTALDH1A1LMNADPYD | |
| SCHEMBL22981334 | 0.71 | GAA (0.40) | GAAMAPTALDH1A1LMNADPYD | |
| SCHEMBL19668130 | 0.71 | GAA (0.40) | GAAMAPTALDH1A1LMNADPYD | |
| SCHEMBL7785411 | 0.71 | MAPT (0.40) | GAAMAPTALDH1A1LMNADPYD | |
| SCHEMBL8933555 | 0.68 | GAA (0.48) | GAAMAPTALDH1A1LMNADPYD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2749641-B1 | CANCER STEM CELL ISOLATION | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2021-06-02 | — | — | EP | disclosed |
| US-10018630-B2 | Cancer stem cell isolation | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2018-07-10 | — | — | US | disclosed |
| US-9434775-B2 | Gene overexpressed in cancer | Aburatani, Hiroyuki (JP) | 2016-09-06 | — | — | US | disclosed |
| US-9376475-B2 | Gene overexpressed in cancer | Aburatani, Hiroyuki (JP) | 2016-06-28 | — | — | US | disclosed |
| US-20140314675-A1 | CANCER STEM CELL ISOLATION | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2014-10-23 | — | — | US | disclosed |
| EP-2749641-A1 | CANCER STEM CELL ISOLATION | Pharmalogicals Research Pte. Ltd. (SG) | 2014-07-02 | — | — | EP | disclosed |
| EP-2311468-B1 | Gene overexpressed in cancer | PERSEUS PROTEOMICS INC (JP) | 2014-01-15 | — | — | EP | disclosed |
| EP-1652923-B1 | GENE OVEREXPRESSED IN CANCER | PERSEUS PROTEOMICS INC (JP) | 2011-10-12 | — | — | EP | disclosed |
| EP-2311468-A1 | Gene overexpressed in cancer | Perseus Proteomics Inc. (JP) | 2011-04-20 | — | — | EP | disclosed |
| US-20110082284-A1 | Gene overexpressed in cancer | ABURANTAI, Hiroyuki (JP) | 2011-04-07 | — | — | US | disclosed |
| US-20080188438-A1 | FRA-1 EXPRESSION IN BRAIN CANCER | THE PENN STATE RESEARCH FOUNDATION (US) | 2008-08-07 | — | — | US | disclosed |
| US-20080153104-A1 | protein encoded by a gene having a nucleotide sequence represented by any of SEQ ID NOs: 1 to 65 or a fragment thereof, an antibody recognizing the protein or antigen-binding fragment thereof, and a polynucleotide having a sequence comprising at least 12 consecutive nucleotides of a nucleotide sequence | HIROYUKI ABURANTAI (JP) | 2008-06-26 | — | — | US | disclosed |
| US-7309487-B2 | Methods and compositions for detecting and treating retinal diseases | UNIVERSITY OF MIAMI | 2007-12-18 | — | — | US | disclosed |
| US-20070037204-A1 | protein encoded by the nucleotide sequence represented by SEQ ID NO: 1 to 65 ; useful for diagnosing and treating cancer | ABURANTAI, Hiroyuki (JP) | 2007-02-15 | — | — | US | disclosed |
| US-7049069-B2 | Detection of urogenital disorders in humans; obtain biological sample, monitor cytokine expression, compare to wild type control, evaluate for urogenital disorders | UNIVERSITY OF FLORIDA (US) | 2006-05-23 | — | — | US | disclosed |
| US-20060099701-A1 | ACTIVATORS OF CYCLIN-DEPENDENT KINASES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2006-05-11 | — | — | US | disclosed |
| EP-1652923-A1 | GENE OVEREXPRESSED IN CANCER | Perseus Proteomics Inc. (JP) | 2006-05-03 | — | — | EP | disclosed |
| US-20050287546-A1 | Novel proteases | SUGEN, INC. | 2005-12-29 | — | — | US | disclosed |
| US-20050176662-A1 | Methods and compositions for detecting and treating retinal diseases | UNIVERSITY OF MIAMI | 2005-08-11 | — | — | US | disclosed |
| US-20040242513-A1 | Tub antisense constructs | JOHANNES-GUTENBERG UNIVERSITAT MAINZ (DE) | 2004-12-02 | — | — | US | disclosed |