Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | DPYD | Q12882 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HBB | P68871 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CPB1 | P15086 | 1/20 | 0.33 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1546530 | 0.85 | GAA (0.41) | GAALMNASMN1; SMN2MAPTDPYD | |
| SCHEMBL103606 | 0.75 | GAA (0.45) | GAALMNASMN1; SMN2MAPTDPYD | |
| SCHEMBL7598527 | 0.74 | HTR2A (0.45) | GAALMNASMN1; SMN2MAPTDPYD | |
| SCHEMBL28699194 | 0.74 | GAA (0.44) | GAALMNASMN1; SMN2MAPTDPYD | |
| SCHEMBL27500671 | 0.74 | ALDH1A1 (0.44) | GAALMNASMN1; SMN2MAPTDPYD | |
| SCHEMBL22981334 | 0.73 | GAA (0.40) | GAALMNASMN1; SMN2MAPTDPYD | |
| SCHEMBL16893950 | 0.72 | GAA (0.54) | GAALMNASMN1; SMN2MAPTDPYD | |
| SCHEMBL18640389 | 0.70 | GAA (0.44) | GAALMNASMN1; SMN2MAPTDPYD | |
| SCHEMBL109259 | 0.70 | GAA (0.40) | GAALMNASMN1; SMN2MAPTDPYD | |
| SCHEMBL19668130 | 0.70 | GAA (0.40) | GAALMNASMN1; SMN2MAPTDPYD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103298475-A | Design of oligonucleotide analogs as therapeutic agents | SPRING BANK PHARMACEUTICALS INC | 2013-09-11 | — | — | CN | disclosed |