SCHEMBL15465892

SCHEMBL15465892

O=C1CCCCN1C(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.43

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.43
FABP5 Q01469 3/20 0.42
FABP7 O15540 2/20 0.42
EPHX2 P34913 1/20 0.41
TSHR P16473 2/20 0.39
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
POLB P06746 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16424441 0.96 KMT2A (0.44) KMT2AFABP5FABP7EPHX2TSHR
SCHEMBL30555288 0.80 TSHR (0.50) KMT2AFABP5FABP7EPHX2TSHR
SCHEMBL30824716 0.80 TSHR (0.50) KMT2AFABP5FABP7EPHX2TSHR
SCHEMBL8222797 0.80 TSHR (0.50) KMT2AFABP5FABP7EPHX2TSHR
SCHEMBL1202245 0.79 KMT2A (0.48) KMT2AFABP5FABP7EPHX2TSHR
SCHEMBL30276687 0.79 TSHR (0.52) KMT2AFABP5FABP7EPHX2TSHR
SCHEMBL30253490 0.79 KMT2A (0.48) KMT2AFABP5FABP7EPHX2TSHR
SCHEMBL31220527 0.79 TSHR (0.52) KMT2AFABP5FABP7EPHX2TSHR
SCHEMBL29617524 0.79 KMT2A (0.48) KMT2AFABP5FABP7EPHX2TSHR
SCHEMBL711979 0.79 TSHR (0.52) KMT2AFABP5FABP7EPHX2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4592275-A2 HYDRAZINYL-PYRROLO COMPOUNDS AND METHODS FOR PRODUCING A CONJUGATE Redwood Bioscience, Inc. (US) 2025-07-30 EP disclosed
US-20250223302-A1 CAMPTOTHECINE ANTIBODY-DRUG CONJUGATES AND METHODS OF USE THEREOF R.P. SCHERER TECHNOLOGIES, LLC 2025-07-10 US disclosed
EP-3074010-B1 HYDRAZINYL-PYRROLO COMPOUNDS AND METHODS FOR PRODUCING A CONJUGATE REDWOOD BIOSCIENCE INC (US) 2025-05-14 EP disclosed
US-12215080-B2 Hydrazinyl-pyrrolo compounds and methods for producing a conjugate REDWOOD BIOSCIENCE, INC. (US) 2025-02-04 US disclosed
US-12187745-B2 Camptothecine antibody-drug conjugates and methods of use thereof R.P. SCHERER TECHNOLOGIES, LLC (US) 2025-01-07 US disclosed
EP-4301415-A1 BRANCHED LINKERS FOR ANTIBODY-DRUG CONJUGATES AND METHODS OF USE THEREOF R.P. Scherer Technologies, LLC (US) 2024-01-10 EP disclosed
CN-116847844-A Camptothecine antibody-drug conjugates and methods of use thereof R.P.谢勒技术有限责任公司 2023-10-03 CN disclosed
US-20230277676-A1 CAMPTOTHECINE ANTIBODY-DRUG CONJUGATES AND METHODS OF USE THEREOF ARES CAPITAL CORPORATION, AS COLLATERAL AGENT 2023-09-07 US disclosed
US-11696904-B2 Prodrug for therapeutic applications THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-07-11 US disclosed
US-11564989-B2 Camptothecine antibody-drug conjugates and methods of use thereof R.P. SCHERER TECHNOLOGIES, LLC (US) 2023-01-31 US disclosed
US-11180451-B2 Hydrazinyl-pyrrolo compounds and methods for producing a conjugate REDWOOD BIOSCIENCE, INC. (US) 2021-11-23 US disclosed
US-20200317610-A1 Hydrazinyl-Pyrrolo Compounds and Methods for Producing a Conjugate ARES CAPITAL CORPORATION, AS COLLATERAL AGENT 2020-10-08 US disclosed
US-10604483-B2 Hydrazinyl-pyrrolo compounds and methods for producing a conjugate REDWOOD BIOSCIENCE, INC. (US) 2020-03-31 US disclosed
US-10464894-B2 Hydrazinyl-pyrrolo compounds and methods for producing a conjugate REDWOOD BIOSCIENCES, INC. (US) 2019-11-05 US disclosed
US-20170049907-A1 HYDRAZINYL-PYRROLO COMPOUNDS AND METHODS FOR PRODUCING A CONJUGATE CATALENT PHARMA SOLUTIONS, LLC 2017-02-23 US disclosed
US-9493413-B2 Hydrazinyl-pyrrolo compounds and methods for producing a conjugate REDWOOD BIOSCIENCE, INC. (US) 2016-11-15 US disclosed
CN-103415540-B The manufacture method of photosensitive composite, cured article and active ray cured article SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2016-03-23 CN disclosed
US-20150157736-A1 HYDRAZINYL-PYRROLO COMPOUNDS AND METHODS FOR PRODUCING A CONJUGATE R.P. SCHERER TECHNOLOGIES, LLC 2015-06-11 US disclosed
US-20140045966-A1 PHOTOSENSITIVE COMPOSITION. CURED ARTICLE, AND METHOD FOR PRODUCING ACTINICALLY CURED ARTICLE SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2014-02-13 US disclosed
CN-103415540-A Photosensitive composition, cured article, and method for producing actinically cured article SANYO CHEMICAL IND LTD 2013-11-27 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150157736-A1 HYDRAZINYL-PYRROLO COMPOUNDS AND METHODS FOR PRODUCING A CONJUGATE DNPEP, QPCT, PDS5A KMT2A 1630/4885FABP5 2313/4885FABP7 2484/4885
US-20170049907-A1 HYDRAZINYL-PYRROLO COMPOUNDS AND METHODS FOR PRODUCING A CONJUGATE DNPEP, QPCT, PDS5A KMT2A 1630/4885FABP5 2313/4885FABP7 2484/4885
US-20230277676-A1 CAMPTOTHECINE ANTIBODY-DRUG CONJUGATES AND METHODS OF USE THEREOF DCTD, ADCY8, ADCY3 KMT2A 1187/4885FABP5 4322/4885FABP7 4234/4885
US-12187745-B2 Camptothecine antibody-drug conjugates and methods of use thereof DCTD, ADCY8, ADCY3 KMT2A 1187/4885FABP5 4322/4885FABP7 4234/4885
US-12215080-B2 Hydrazinyl-pyrrolo compounds and methods for producing a conjugate DNPEP, QPCT, PDS5A KMT2A 1630/4885FABP5 2313/4885FABP7 2484/4885
US-11696904-B2 Prodrug for therapeutic applications S1PR2, S1PR5, S1PR4 KMT2A 1443/4885FABP5 2450/4885FABP7 986/4885
US-20250223302-A1 CAMPTOTHECINE ANTIBODY-DRUG CONJUGATES AND METHODS OF USE THEREOF DCTD, ADCY8, ADCY3 KMT2A 1187/4885FABP5 4322/4885FABP7 4234/4885
US-11180451-B2 Hydrazinyl-pyrrolo compounds and methods for producing a conjugate DNPEP, QPCT, PDS5A KMT2A 1630/4885FABP5 2313/4885FABP7 2484/4885
US-10464894-B2 Hydrazinyl-pyrrolo compounds and methods for producing a conjugate DNPEP, QPCT, PDS5A KMT2A 1630/4885FABP5 2313/4885FABP7 2484/4885
US-10604483-B2 Hydrazinyl-pyrrolo compounds and methods for producing a conjugate DNPEP, QPCT, PDS5A KMT2A 1630/4885FABP5 2313/4885FABP7 2484/4885
US-20200317610-A1 Hydrazinyl-Pyrrolo Compounds and Methods for Producing a Conjugate DNPEP, QPCT, PDS5A KMT2A 1630/4885FABP5 2313/4885FABP7 2484/4885
US-11564989-B2 Camptothecine antibody-drug conjugates and methods of use thereof DCTD, ADCY8, ADCY3 KMT2A 1187/4885FABP5 4322/4885FABP7 4234/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.