SCHEMBL15466914

SCHEMBL15466914

C1=CC2CC1CC2C1CCC2CCCC2C1

nearest known ligand 0.30

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.30
GAA P10253 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15466703 0.96 ALDH1A1 (0.32) ALDH1A1GAATDP1
SCHEMBL7535152 0.87 KDM4E (0.32) ALDH1A1GAATDP1
SCHEMBL409464 0.83 HSD11B1 (0.32) ALDH1A1GAATDP1
SCHEMBL15467476 0.82
SCHEMBL249375 0.81 HSD11B1 (0.35) ALDH1A1GAATDP1
SCHEMBL250942 0.81 HSD11B1 (0.35) ALDH1A1GAATDP1
SCHEMBL28367030 0.76 EPAS1 (0.30)
SCHEMBL11983382 0.76 ALDH1A1 (0.30) ALDH1A1GAATDP1
SCHEMBL15467512 0.75 ALDH1A1 (0.35) ALDH1A1GAATDP1
SCHEMBL15467757 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10227433-B2 Cycloalkylnorbornene monomers, polymers derived therefrom and their use in pervaporation PROMERUS, LLC (US) 2019-03-12 US disclosed
US-20160369026-A1 CYCLOALKYLNORBORNENE MONOMERS, POLYMERS DERIVED THEREFROM AND THEIR USE IN PERVAPORATION PROMERUS, LLC (US) 2016-12-22 US disclosed
US-9468890-B2 Cycloalkylnorbornene monomers, polymers derived therefrom and their use in pervaporation PROMERUS, LLC (US) 2016-10-18 US disclosed
EP-2870129-B1 CYCLOALKYLNORBORNENE MONOMERS, POLYMERS DERIVED THEREFROM AND THEIR USE IN PERVAPORATION SUMITOMO BAKELITE CO (JP) 2016-04-06 EP disclosed
US-20140042090-A1 CYCLOALKYLNORBORNENE MONOMERS, POLYMERS DERIVED THEREFROM AND THEIR USE IN PERVAPORATION PROMERUS, LLC (US) 2014-02-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160369026-A1 CYCLOALKYLNORBORNENE MONOMERS, POLYMERS DERIVED THEREFROM AND THEIR USE IN PERVAPORATION NOTUM, AGPS, WEE1 ALDH1A1 3394/4885GAA 2851/4885TDP1 2684/4885
US-10227433-B2 Cycloalkylnorbornene monomers, polymers derived therefrom and their use in pervaporation NOTUM, AGPS, WEE1 ALDH1A1 3394/4885GAA 2851/4885TDP1 2684/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.