⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7535152 | 0.86 | KDM4E (0.32) | — | |
| SCHEMBL15466914 | 0.82 | ALDH1A1 (0.30) | — | |
| SCHEMBL409464 | 0.81 | HSD11B1 (0.32) | — | |
| SCHEMBL250942 | 0.79 | HSD11B1 (0.35) | — | |
| SCHEMBL249375 | 0.79 | HSD11B1 (0.35) | — | |
| SCHEMBL15466703 | 0.78 | ALDH1A1 (0.32) | — | |
| SCHEMBL15467512 | 0.78 | ALDH1A1 (0.35) | — | |
| SCHEMBL15467232 | 0.77 | ALDH1A1 (0.33) | — | |
| SCHEMBL15466596 | 0.74 | MAPT (0.33) | — | |
| SCHEMBL28367030 | 0.74 | EPAS1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10227433-B2 | Cycloalkylnorbornene monomers, polymers derived therefrom and their use in pervaporation | PROMERUS, LLC (US) | 2019-03-12 | — | — | US | disclosed |
| US-20160369026-A1 | CYCLOALKYLNORBORNENE MONOMERS, POLYMERS DERIVED THEREFROM AND THEIR USE IN PERVAPORATION | PROMERUS, LLC (US) | 2016-12-22 | — | — | US | disclosed |
| US-9468890-B2 | Cycloalkylnorbornene monomers, polymers derived therefrom and their use in pervaporation | PROMERUS, LLC (US) | 2016-10-18 | — | — | US | disclosed |
| US-20140042090-A1 | CYCLOALKYLNORBORNENE MONOMERS, POLYMERS DERIVED THEREFROM AND THEIR USE IN PERVAPORATION | PROMERUS, LLC (US) | 2014-02-13 | — | — | US | disclosed |