Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15427811 | 0.83 | ERN1 (0.42) | ERN1POLBPTPN1MEN1KMT2A | |
| SCHEMBL30439279 | 0.83 | CA1 (0.47) | ERN1POLBPTPN1MEN1KMT2A | |
| SCHEMBL7193571 | 0.83 | CA1 (0.47) | ERN1POLBPTPN1MEN1KMT2A | |
| SCHEMBL15428211 | 0.79 | TDP1 (0.47) | ERN1POLBPTPN1MEN1KMT2A | |
| SCHEMBL30134862 | 0.79 | TDP1 (0.47) | ERN1POLBPTPN1MEN1KMT2A | |
| SCHEMBL3249045 | 0.76 | CYP1A2 (0.54) | MEN1KMT2ACYP2A6ALDH1A1TDP1 | |
| SCHEMBL29521593 | 0.75 | DNMT1 (0.48) | ERN1POLBPTPN1MEN1KMT2A | |
| SCHEMBL7643518 | 0.75 | DNMT1 (0.48) | ERN1POLBPTPN1MEN1KMT2A | |
| Acetic Acid SCHEMBL11404458 | 0.75 | CYP1A2 (0.46) | ERN1MEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL3441131 | 0.74 | ALDH1A1 (0.46) | MEN1KMT2ACYP2A6ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140046086-A1 | PROCESS FOR THE PREPARATION OF TAFLUPROST AND INTERMEDIATES THEREOF | SCINOPHARM (CHANGSHU) PHARMACEUTICALS, LTD. (CN) | 2014-02-13 | — | — | US | disclosed |
| WO-2014023256-A1 | PROCESS FOR PREPARATION OF TAFLUPROST AND INTERMEDIATES THEREOF | SCINOPHARM (CHANGSHU) PHARMACEUTICALS, LTD. (CN) | 2014-02-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140046086-A1 | PROCESS FOR THE PREPARATION OF TAFLUPROST AND INTERMEDIATES THEREOF | PTGIS, PTGES, PTGES3 | ERN1 1644/4885POLB 1686/4885PTPN1 3942/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.