SCHEMBL15467792

SCHEMBL15467792

OC(c1ccc(C2CC3C=CC2C3)cc1)(C(F)(F)F)C(F)(F)F

nearest known ligand 0.41

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
RORC P51449 7/20 0.40
NR1H2 P55055 10/20 0.39
NR1H3 Q13133 10/20 0.39
NR1I2 O75469 1/20 0.36
MLYCD O95822 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL147518 0.83 HTR2C (0.47)
SCHEMBL6234699 0.79 KDM1A (0.38)
SCHEMBL16530012 0.79 KDM1A (0.38)
SCHEMBL1739179 0.77 KDM1A (0.38)
SCHEMBL21525760 0.75 KDM1A (0.42)
SCHEMBL21525759 0.75 KDM1A (0.42)
SCHEMBL1868041 0.74 KDM1A (0.50)
SCHEMBL3296262 0.73 LMNA (0.34)
SCHEMBL912758 0.71 HTR2A (0.43)
SCHEMBL12997456 0.71 KDM1A (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10227433-B2 Cycloalkylnorbornene monomers, polymers derived therefrom and their use in pervaporation PROMERUS, LLC (US) 2019-03-12 US disclosed
US-10227433-B2 Cycloalkylnorbornene monomers, polymers derived therefrom and their use in pervaporation PROMERUS, LLC (US) 2019-03-12 US disclosed
US-20160369026-A1 CYCLOALKYLNORBORNENE MONOMERS, POLYMERS DERIVED THEREFROM AND THEIR USE IN PERVAPORATION PROMERUS, LLC (US) 2016-12-22 US disclosed
US-20160369026-A1 CYCLOALKYLNORBORNENE MONOMERS, POLYMERS DERIVED THEREFROM AND THEIR USE IN PERVAPORATION PROMERUS, LLC (US) 2016-12-22 US disclosed
US-20160369026-A1 CYCLOALKYLNORBORNENE MONOMERS, POLYMERS DERIVED THEREFROM AND THEIR USE IN PERVAPORATION PROMERUS, LLC (US) 2016-12-22 US disclosed
US-9468890-B2 Cycloalkylnorbornene monomers, polymers derived therefrom and their use in pervaporation PROMERUS, LLC (US) 2016-10-18 US disclosed
US-9468890-B2 Cycloalkylnorbornene monomers, polymers derived therefrom and their use in pervaporation PROMERUS, LLC (US) 2016-10-18 US disclosed
US-9468890-B2 Cycloalkylnorbornene monomers, polymers derived therefrom and their use in pervaporation PROMERUS, LLC (US) 2016-10-18 US disclosed
EP-2870129-B1 CYCLOALKYLNORBORNENE MONOMERS, POLYMERS DERIVED THEREFROM AND THEIR USE IN PERVAPORATION SUMITOMO BAKELITE CO (JP) 2016-04-06 EP disclosed
EP-2870129-B1 CYCLOALKYLNORBORNENE MONOMERS, POLYMERS DERIVED THEREFROM AND THEIR USE IN PERVAPORATION SUMITOMO BAKELITE CO (JP) 2016-04-06 EP disclosed
US-20140042090-A1 CYCLOALKYLNORBORNENE MONOMERS, POLYMERS DERIVED THEREFROM AND THEIR USE IN PERVAPORATION PROMERUS, LLC (US) 2014-02-13 US disclosed
US-20140042090-A1 CYCLOALKYLNORBORNENE MONOMERS, POLYMERS DERIVED THEREFROM AND THEIR USE IN PERVAPORATION PROMERUS, LLC (US) 2014-02-13 US disclosed
US-20140042090-A1 CYCLOALKYLNORBORNENE MONOMERS, POLYMERS DERIVED THEREFROM AND THEIR USE IN PERVAPORATION PROMERUS, LLC (US) 2014-02-13 US disclosed
WO-2014025735-A1 CYCLOALKYLNORBORNENE MONOMERS, POLYMERS DERIVED THEREFROM AND THEIR USE IN PERVAPORATION PROMERUS, LLC (US) 2014-02-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160369026-A1 CYCLOALKYLNORBORNENE MONOMERS, POLYMERS DERIVED THEREFROM AND THEIR USE IN PERVAPORATION NOTUM, AGPS, WEE1 RORC 3350/4885NR1H2 481/4885NR1H3 329/4885
US-10227433-B2 Cycloalkylnorbornene monomers, polymers derived therefrom and their use in pervaporation NOTUM, AGPS, WEE1 RORC 3350/4885NR1H2 481/4885NR1H3 329/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.