Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | CCL2 | P13500 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
| ▸ | G6PD | P11413 | 1/20 | 0.33 |
| ▸ | CCR6 | P51684 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | HTR2B | P41595 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15468333 | 0.74 | HTR2A (0.40) | PRCPBRD4CCL2NOTUMOPRM1 | |
| SCHEMBL10060256 | 0.71 | PRCP (0.38) | PRCPBRD4CCL2NOTUMOPRM1 | |
| SCHEMBL14392106 | 0.71 | PRCP (0.38) | PRCPBRD4CCL2NOTUMOPRM1 | |
| SCHEMBL10079646 | 0.70 | OPRM1 (0.35) | PRCPOPRM1HTR2A | |
| SCHEMBL10060283 | 0.70 | OPRM1 (0.35) | PRCPOPRM1HTR2A | |
| SCHEMBL10079284 | 0.67 | OPRM1 (0.42) | PRCPOPRM1HTR2AHTR2CHTR2B | |
| SCHEMBL13309683 | 0.66 | AADAT (0.40) | OPRM1NSD2G6PDCCR6 | |
| SCHEMBL22861976 | 0.65 | BRD4 (0.45) | BRD4CCL2OPRM1HTR2AHTR2C | |
| SCHEMBL12747479 | 0.64 | ACE (0.40) | NSD2G6PDCCR6HTR2AHTR2C | |
| SCHEMBL14170111 | 0.64 | BRD4 (0.38) | PRCPBRD4NOTUMOPRM1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8648094-B2 | IAP BIR domain binding compounds | PHARMASCIENCE, INC. (CA) | 2014-02-11 | — | — | US | disclosed |