SCHEMBL15468508

SCHEMBL15468508

CC(CCl)CC(C)c1ccccc1N

nearest known ligand 0.35

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 3/20 0.35
TSHR P16473 2/20 0.33
ALDH1A1 P00352 1/20 0.33
CYP3A4 P08684 2/20 0.32
ALOX15 P16050 1/20 0.32
CASP1 P29466 1/20 0.32
CASP7 P55210 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
TAAR1 Q96RJ0 2/20 0.31
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22156385 0.83 TSHR (0.42) TRPA1TSHRALDH1A1CYP3A4ALOX15
SCHEMBL708994 0.80 ALDH1A1 (0.38) TSHRALDH1A1CYP3A4ALOX15CASP1
SCHEMBL21081220 0.80 TSHR (0.40) TRPA1TSHRALDH1A1CYP3A4ALOX15
SCHEMBL3766807 0.76 TSHR (0.40) TRPA1TSHRALDH1A1CYP3A4ALOX15
SCHEMBL3820403 0.74 TSHR (0.59) TSHRALDH1A1CYP3A4ALOX15CASP1
SCHEMBL7868990 0.74 TAAR1 (0.52) TSHRALDH1A1CYP3A4ALOX15CASP1
SCHEMBL111291 0.74 TSHR (0.59) TSHRALDH1A1CYP3A4ALOX15CASP1
SCHEMBL10598514 0.72 TRPA1 (0.64) TRPA1TSHRALDH1A1TAAR1
SCHEMBL8573119 0.72 TSHR (0.42) TRPA1TSHRALDH1A1CYP3A4ALOX15
SCHEMBL10589371 0.72 TSHR (0.38) TSHRALDH1A1CYP3A4ALOX15CASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2192115-B1 1,3-DIMETHYLBUTYLCARBOXANILIDES FOR CONTROLLING UNDESIRABLE MICRO-ORGANISMS BAYER CROPSCIENCE AG (DE) 2014-02-12 EP disclosed