Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL111291 | 1.00 | TSHR (0.59) | TSHRALDH1A1ALOX15USP2GAA | |
| SCHEMBL22156385 | 0.84 | TSHR (0.42) | TSHRALDH1A1ALOX15USP2GAA | |
| SCHEMBL994607 | 0.83 | TSHR (0.73) | TSHRGABRA1GABRB2KDM4EL3MBTL1 | |
| SCHEMBL4555367 | 0.83 | ALDH1A1 (0.41) | TSHRALDH1A1ALOX15USP2GAA | |
| SCHEMBL7868990 | 0.82 | TAAR1 (0.52) | TSHRALDH1A1ALOX15CYP3A4CASP1 | |
| SCHEMBL2476981 | 0.81 | TSHR (0.48) | TSHRALDH1A1ALOX15USP2GAA | |
| SCHEMBL3766807 | 0.81 | TSHR (0.40) | TSHRALDH1A1ALOX15USP2GAA | |
| SCHEMBL708994 | 0.80 | ALDH1A1 (0.38) | TSHRALDH1A1ALOX15HSD17B10CYP3A4 | |
| SCHEMBL10589371 | 0.80 | TSHR (0.38) | TSHRALDH1A1ALOX15CYP3A4CASP1 | |
| SCHEMBL8573119 | 0.80 | TSHR (0.42) | TSHRALDH1A1ALOX15HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0987332-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE AMINO COMPOUNDS | Kaneka Corporation (JP) | 2000-03-22 | — | — | EP | claimed |
| EP-4328229-A2 | SUBSTITUTED HETEROCYCLIC FUSED CYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USE THEREOF | Genfleet Therapeutics (Shanghai) Inc. (CN) | 2024-02-28 | — | — | EP | disclosed |
| US-8318733-B2 | Modulators of ATP-binding cassette transporters | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2012-11-27 | — | — | US | disclosed |
| EP-0987332-B1 | DNA encoding a polypeptide having stereoselective transaminase activity, and transformants comprising said DNA | KANEKA CORP (JP) | 2009-08-19 | — | — | EP | disclosed |
| US-7169592-B2 | Producing optically active amino compounds | KANEKA CORPORATION (JP) | 2007-01-30 | — | — | US | disclosed |
| US-20020192786-A1 | Producing optically active amino compounds | KANEKA CORPORATION | 2002-12-19 | — | — | US | disclosed |
| EP-0987332-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE AMINO COMPOUNDS | Kaneka Corporation (JP) | 2000-03-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020192786-A1 | Producing optically active amino compounds | TKT, GOT1, AADAT | TSHR 1107/4885ALDH1A1 151/4885ALOX15 2382/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.