Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HINT1 | P49773 | 1/20 | 0.53 |
| ▸ | TGM2 | P21980 | 1/20 | 0.50 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.49 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.49 |
| ▸ | NT5E | P21589 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | FUT6 | P51993 | 2/20 | 0.45 |
| ▸ | KRAS | P01116 | 4/20 | 0.45 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13522448 | 1.00 | HINT1 (0.53) | HINT1TGM2TAS1R3TAS1R1NT5E | |
| SCHEMBL13522424 | 1.00 | HINT1 (0.53) | HINT1TGM2TAS1R3TAS1R1NT5E | |
| SCHEMBL18744143 | 1.00 | HINT1 (0.53) | HINT1TGM2TAS1R3TAS1R1NT5E | |
| SCHEMBL15468734 | 1.00 | HINT1 (0.53) | HINT1TGM2TAS1R3TAS1R1NT5E | |
| SCHEMBL15788429 | 1.00 | HINT1 (0.53) | HINT1TGM2TAS1R3TAS1R1NT5E | |
| SCHEMBL17232119 | 0.89 | HINT1 (0.49) | HINT1TGM2TAS1R3TAS1R1NT5E | |
| SCHEMBL18744142 | 0.88 | HINT1 (0.48) | HINT1TGM2TAS1R3TAS1R1NT5E | |
| SCHEMBL14143192 | 0.86 | HINT1 (0.46) | HINT1TGM2TAS1R3TAS1R1NT5E | |
| SCHEMBL14769878 | 0.86 | HINT1 (0.49) | HINT1TGM2TAS1R3TAS1R1NT5E | |
| SCHEMBL15468735 | 0.86 | NT5E (0.57) | HINT1TGM2TAS1R3TAS1R1NT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2307434-B1 | COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF VIRAL INFECTIONS | IDENIX PHARMACEUTICALS INC (US) | 2014-02-12 | — | — | EP | disclosed |