Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRN | P28799 | 1/20 | 0.45 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 2/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15469260 | 0.86 | GRN (0.43) | GRNSORT1ALDH1A1BCHEACHE | |
| SCHEMBL16281027 | 0.84 | HSD11B1 (0.43) | ALDH1A1TSHRKDM4EGLAHPGD | |
| SCHEMBL15473180 | 0.83 | CYP19A1 (0.42) | ALDH1A1TSHRKDM4EGLAHPGD | |
| SCHEMBL15469274 | 0.80 | GRN (0.41) | GRNSORT1ALDH1A1GAAKMT2A | |
| SCHEMBL2507561 | 0.77 | SLC7A5 (0.51) | PKM | |
| SCHEMBL2503881 | 0.77 | SLC7A5 (0.51) | PKM | |
| SCHEMBL2503889 | 0.77 | SLC7A5 (0.51) | PKM | |
| SCHEMBL1691046 | 0.72 | GRN (0.47) | GRNSORT1MAPT | |
| SCHEMBL15473179 | 0.70 | F2 (0.45) | ALDH1A1HPGDGAABCHEACHE | |
| SCHEMBL15469259 | 0.70 | MEN1 (0.46) | GRNSORT1ALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8907045-B2 | Biocompatible adhesive polymers | EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) | 2014-12-09 | — | — | US | disclosed |
| US-20140041802-A1 | BIOCOMPATIBLE ADHESIVE POLYMERS | EMPIRE TECHNOLOGY DEVELOPMENT LLC | 2014-02-13 | — | — | US | disclosed |