SCHEMBL15469274

SCHEMBL15469274

CC(C)(C)Cc1cn(C(=O)c2ccccc2)cn1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRN P28799 1/20 0.41
SORT1 Q99523 1/20 0.41
FDPS P14324 1/20 0.39
POLB P06746 2/20 0.36
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
BLM P54132 1/20 0.35
NAMPT P43490 1/20 0.34
GAA P10253 2/20 0.34
CPB1 P15086 1/20 0.33
CPB2 Q96IY4 1/20 0.33
SLC6A7 Q99884 1/20 0.33
NPC1 O15118 1/20 0.33
TP53 P04637 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
KDM4A O75164 1/20 0.33
KDM5A P29375 1/20 0.33
KDM4C Q9H3R0 1/20 0.33
KDM5B Q9UGL1 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15473181 0.83 BLM (0.41) FDPSKMT2ABLMNAMPTSLC6A7
SCHEMBL15469273 0.80 GRN (0.45) GRNSORT1MEN1KMT2AGAA
SCHEMBL6892982 0.79 NAMPT (0.40) FDPSPOLBMEN1KMT2ANAMPT
SCHEMBL9525142 0.74 MAPT (0.41) MEN1KMT2AGAASLC6A7NPC1
SCHEMBL11612941 0.73 MAPK1 (0.35) FDPSPOLBMEN1KMT2ABLM
SCHEMBL6896811 0.70 KDM5A (0.36) POLBMEN1KMT2AGAACPB1
SCHEMBL11148260 0.68 CPB2 (0.44) CPB1CPB2
SCHEMBL10187011 0.68 SIRT2 (0.46) GRNSORT1
SCHEMBL1691046 0.68 GRN (0.47) GRNSORT1POLBCPB2NPC1
SCHEMBL15469259 0.66 MEN1 (0.46) GRNSORT1POLBMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8907045-B2 Biocompatible adhesive polymers EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2014-12-09 US disclosed
US-20140041802-A1 BIOCOMPATIBLE ADHESIVE POLYMERS EMPIRE TECHNOLOGY DEVELOPMENT LLC 2014-02-13 US disclosed