SCHEMBL15469259

SCHEMBL15469259

CC(C)(C)Cc1cn(CCc2ccccc2)cn1

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
GRN P28799 2/20 0.39
SORT1 Q99523 2/20 0.39
HTT P42858 1/20 0.39
HMOX1 P09601 1/20 0.38
CNOT7 Q9UIV1 1/20 0.36
EPHX2 P34913 1/20 0.35
ALDH1A1 P00352 1/20 0.35
POLB P06746 1/20 0.35
HIF1A Q16665 1/20 0.35
KDM4C Q9H3R0 1/20 0.34
SLC6A3 Q01959 1/20 0.34
ADORA2A P29274 1/20 0.34
KDM5A P29375 1/20 0.34
KDM5B Q9UGL1 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1691046 0.84 GRN (0.47) GRNSORT1POLBKDM4CKDM5A
SCHEMBL15473178 0.83 HTT (0.41) MEN1KMT2AHTTHMOX1ALDH1A1
SCHEMBL8862886 0.80 HTT (0.41) HTTHMOX1CNOT7KDM4CSLC6A3
SCHEMBL6616681 0.76 LTA4H (0.38) KMT2AALDH1A1
SCHEMBL28800303 0.76 QPCT (0.44) KMT2AHTTHMOX1CNOT7ALDH1A1
SCHEMBL15469260 0.73 GRN (0.43) MEN1KMT2AGRNSORT1HTT
SCHEMBL15459562 0.73 CPB2 (0.39)
SCHEMBL27558570 0.72 HTT (0.44) KMT2AHTTHMOX1CNOT7POLB
SCHEMBL21198915 0.72 ADORA2A (0.44) HTTHMOX1SLC6A3ADORA2A
SCHEMBL28802435 0.71 HPGDS (0.55) HTTHMOX1KDM4CKDM5AKDM5B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8907045-B2 Biocompatible adhesive polymers EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2014-12-09 US disclosed
US-20140041802-A1 BIOCOMPATIBLE ADHESIVE POLYMERS EMPIRE TECHNOLOGY DEVELOPMENT LLC 2014-02-13 US disclosed