SCHEMBL15469292

SCHEMBL15469292

CC1(C)c2ccccc2-c2ccc(N3c4ccc(-c5ccc6ccccc6c5)cc4C(C)(C)c4cc(-c5cccc6ccccc56)ccc43)cc21

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIM1 P11309 2/20 0.34
MET P08581 1/20 0.34
AR P10275 1/20 0.34
PGR P06401 2/20 0.32
SLC6A2 P23975 1/20 0.32
SLC6A4 P31645 1/20 0.32
SLC6A3 Q01959 1/20 0.32
KDM4E B2RXH2 1/20 0.32
MEN1 O00255 1/20 0.32
MAPT P10636 1/20 0.32
MAPK1 P28482 1/20 0.32
KMT2A Q03164 1/20 0.32
CNR2 P34972 1/20 0.32
MCL1 Q07820 1/20 0.32
ACMSD Q8TDX5 1/20 0.32
ENPP3 O14638 1/20 0.32
ENPP1 P22413 1/20 0.32
CA12 O43570 3/20 0.31
CA1 P00915 3/20 0.31
CA2 P00918 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15495043 0.94 AR (0.36) ARPGRSLC6A2SLC6A4SLC6A3
SCHEMBL15469339 0.92 AR (0.35) ARPGRSLC6A2SLC6A4SLC6A3
SCHEMBL16547127 0.90 AKT1 (0.34) ARPGRSLC6A2SLC6A4SLC6A3
SCHEMBL15469337 0.89 ALDH1A1 (0.38) ARPGRSLC6A2SLC6A4SLC6A3
SCHEMBL15463932 0.88 AR (0.33) ARPGRSLC6A2SLC6A4SLC6A3
SCHEMBL15469265 0.88 PDE6D (0.38) PIM1METSLC6A2SLC6A4SLC6A3
SCHEMBL19042616 0.87 MEN1 (0.34) ARPGRSLC6A2SLC6A4SLC6A3
SCHEMBL15469341 0.87 PDK2 (0.39) ARPGR
SCHEMBL15469338 0.85 PDK2 (0.39) ARPGRKMT2ACYP1A2CYP2C9
SCHEMBL15469300 0.85 PDK2 (0.39) ARPGRKMT2ACYP1A2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9905770-B2 Compound having acridan ring structure, and organic electroluminescent device HODOGAYA CHEMICAL CO., LTD. (JP) 2018-02-27 US disclosed
US-9905770-B2 Compound having acridan ring structure, and organic electroluminescent device HODOGAYA CHEMICAL CO., LTD. (JP) 2018-02-27 US disclosed
EP-2703388-A1 COMPOUND WITH ACRIDAN RING STRUCTURE, AND ORGANIC ELECTROLUMINESCENT ELEMENT Hodogaya Chemical Co., Ltd. (JP) 2014-03-05 EP disclosed
US-20140042425-A1 COMPOUND HAVING ACRIDAN RING STRUCTURE, AND ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2014-02-13 US disclosed
US-20140042425-A1 COMPOUND HAVING ACRIDAN RING STRUCTURE, AND ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2014-02-13 US disclosed