Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.38 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | GPR142 | Q7Z601 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | PPARA | Q07869 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15469579 | 0.90 | CHRNB2 (0.32) | ALDH1A1F2GLAHPGDPARP1 | |
| SCHEMBL12822455 | 0.89 | RIOK2 (0.31) | ALDH1A1F2GLAHPGD | |
| SCHEMBL15469566 | 0.87 | ADORA2A (0.33) | ADORA2AIMPDH2CNR1CNR2HDAC6 | |
| SCHEMBL15469613 | 0.87 | ADORA2A (0.37) | ADORA2AIMPDH2ALDH1A1CNR1CNR2 | |
| SCHEMBL15469567 | 0.86 | ADORA2A (0.40) | ADORA2AIMPDH2ALDH1A1CNR1CNR2 | |
| SCHEMBL15469572 | 0.86 | HDAC6 (0.35) | ADORA2AIMPDH2CNR1CNR2HDAC6 | |
| SCHEMBL15469570 | 0.86 | ADORA2A (0.33) | ADORA2AIMPDH2CNR1CNR2HDAC6 | |
| SCHEMBL632771 | 0.86 | HPGDS (0.36) | ALDH1A1LMNAF2GLAHPGD | |
| SCHEMBL15469576 | 0.86 | ALDH1A1 (0.42) | ADORA2AIMPDH2ALDH1A1CNR1CNR2 | |
| SCHEMBL15469594 | 0.86 | PDGFRB (0.34) | ALDH1A1F2GLAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140045890-A1 | NOVEL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-02-13 | — | — | US | disclosed |
| US-20140045890-A1 | NOVEL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140045890-A1 | NOVEL COMPOUNDS | CYP1B1, CYP1A1, CYP51A1 | ADORA2A 4193/4885IMPDH2 1505/4885ALDH1A1 248/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.