SCHEMBL22958742

SCHEMBL22958742

c1ccc(-c2ccc3c(c2)Oc2cc(-c4ccccc4-c4ccc(-c5cccc6c5sc5ccccc56)cc4)cc4c2N3c2ccccc2O4)cc1

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.42
PRKDC P78527 3/20 0.38
TNKS O95271 1/20 0.33
TNKS2 Q9H2K2 1/20 0.33
PIK3CD O00329 1/20 0.32
BRD4 O60885 1/20 0.32
PIK3CA P42336 1/20 0.32
PIK3CB P42338 1/20 0.32
MTOR P42345 1/20 0.32
PIK3CG P48736 1/20 0.32
KCNH2 Q12809 1/20 0.32
BRDT Q58F21 1/20 0.32
LIMK1 P53667 2/20 0.32
PARP14 Q460N5 1/20 0.31
F9 P00740 1/20 0.31
ADK P55263 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22958758 0.94 ALOX5 (0.47) ALOX5PRKDCTNKSTNKS2PIK3CD
SCHEMBL22958743 0.93 ALOX5 (0.49) ALOX5PRKDCTNKSTNKS2PIK3CD
SCHEMBL22958710 0.91 ALOX5 (0.40) ALOX5PRKDCPIK3CDBRD4PIK3CA
SCHEMBL15470278 0.90 ALOX5 (0.44) ALOX5PRKDCTNKSTNKS2PIK3CD
SCHEMBL22958677 0.87 ALOX5 (0.40) ALOX5PRKDC
SCHEMBL13827532 0.86 ALOX5 (0.47) ALOX5PRKDCTNKSTNKS2PIK3CD
SCHEMBL15470276 0.86 ALOX5 (0.46) ALOX5PRKDCTNKSTNKS2PIK3CD
SCHEMBL15469927 0.84 ALOX5 (0.39) ALOX5PRKDCTNKSTNKS2PIK3CD
SCHEMBL22958696 0.83 MGLL (0.35)
SCHEMBL15469877 0.82 ALOX5 (0.39) ALOX5PRKDCPIK3CDBRD4PIK3CA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210043852-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2021-02-11 US disclosed