Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 8/20 | 0.46 |
| ▸ | MEN1 | O00255 | 7/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.46 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | HPGD | P15428 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | APAF1 | O14727 | 1/20 | 0.46 |
| ▸ | TDP2 | O95551 | 1/20 | 0.46 |
| ▸ | NSD2 | O96028 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13731660 | 0.72 | MAPT (0.68) | GAAMEN1KMT2AMAPTHPGD | |
| SCHEMBL24430068 | 0.67 | RGS4 (0.45) | GAAMEN1KMT2AMAPTHPGD | |
| SCHEMBL3443278 | 0.67 | KMT2A (0.44) | GAAKMT2AMAPTHPGDKDM4E | |
| SCHEMBL24430071 | 0.66 | RGS4 (0.44) | GAAMEN1KMT2AMAPTHPGD | |
| SCHEMBL1010796 | 0.66 | ALDH1A1 (0.46) | MEN1KMT2AMAPTHPGDKDM4E | |
| SCHEMBL24430055 | 0.65 | RGS4 (0.43) | GAAMEN1KMT2AMAPTHPGD | |
| SCHEMBL24429996 | 0.65 | ALDH1A1 (0.44) | GAAMEN1KMT2AMAPTHPGD | |
| SCHEMBL7773988 | 0.65 | GAA (0.50) | GAAMEN1KMT2AMAPTKDM4E | |
| SCHEMBL9326744 | 0.65 | NPC1 (0.43) | GAAMAPTKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL304891 | 0.64 | CXCR2 (0.54) | GAAMEN1KMT2AMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140045689-A1 | 3,4-disubstituted pyrrole 2,5-diones and their use as fungicides | BASF SE (DE) | 2014-02-13 | — | — | US | disclosed |
| US-20140045689-A1 | 3,4-disubstituted pyrrole 2,5-diones and their use as fungicides | BASF SE (DE) | 2014-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140045689-A1 | 3,4-disubstituted pyrrole 2,5-diones and their use as fungicides | CYP51A1, DDT, DPM1 | GAA 1263/4885MEN1 1295/4885KMT2A 2683/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.