Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | BLM | P54132 | 2/20 | 0.46 |
| ▸ | GMNN | O75496 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | THPO | P40225 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | CTSG | P08311 | 1/20 | 0.40 |
| ▸ | CTRC | Q99895 | 1/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | XIAP | P98170 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4011867 | 0.74 | ALDH1A1 (0.48) | ALDH1A1BLMGMNNLMNAMAPT | |
| SCHEMBL20216186 | 0.74 | ALDH1A1 (0.48) | ALDH1A1BLMGMNNLMNAMAPT | |
| SCHEMBL14136363 | 0.73 | ALDH1A1 (0.46) | ALDH1A1BLMGMNNLMNAMAPT | |
| SCHEMBL988699 | 0.73 | ALDH1A1 (0.46) | ALDH1A1BLMGMNNLMNAMAPT | |
| SCHEMBL3470129 | 0.73 | RGS4 (0.53) | ALDH1A1BLMGMNNLMNAMAPT | |
| SCHEMBL27607300 | 0.72 | POLB (0.42) | ALDH1A1BLMGMNNLMNAMAPT | |
| SCHEMBL6809868 | 0.71 | RGS4 (0.48) | ALDH1A1BLMGMNNLMNAMAPT | |
| SCHEMBL3691142 | 0.71 | ALDH1A1 (0.36) | ALDH1A1BLMGMNNLMNAMAPT | |
| SCHEMBL4741750 | 0.71 | MGLL (0.44) | ALDH1A1BLMGMNNLMNAMAPT | |
| SCHEMBL25197755 | 0.71 | GMNN (0.40) | ALDH1A1BLMGMNNLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110117009-A1 | DRUG CONJUGATES WITH POLYGLYCEROLS | FREIE UNIVERSITÄT BERLIN (DE) | 2011-05-19 | — | — | US | disclosed |
| EP-2268315-A1 | DRUG CONJUGATES WITH POLYGLYCEROLS | Freie Universität Berlin (DE) | 2011-01-05 | — | — | EP | disclosed |
| EP-2216049-A1 | Drug conjugates with polyglycerols | Freie Universität Berlin (DE) | 2010-08-11 | — | — | EP | disclosed |
| WO-2009121564-A1 | DRUG CONJUGATES WITH POLYGLYCEROLS | FREIE UNIVERSITÄT BERLIN (DE) | 2009-10-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110117009-A1 | DRUG CONJUGATES WITH POLYGLYCEROLS | DDOST, STT3A, STT3B | ALDH1A1 2528/4885BLM 4256/4885GMNN 308/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.