Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.49 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.49 |
| ▸ | HSD17B3 | P37058 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 5/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4828359 | 0.94 | HTT (0.51) | GABRA1GABRB2HSD17B3MEN1KMT2A | |
| SCHEMBL7762871 | 0.93 | HTT (0.53) | HSD17B3MEN1KMT2AHTTTSHR | |
| SCHEMBL599569 | 0.93 | HTT (0.53) | HSD17B3MEN1KMT2AHTTTSHR | |
| SCHEMBL6552351 | 0.93 | HTT (0.53) | HSD17B3MEN1KMT2AHTTTSHR | |
| SCHEMBL875305 | 0.93 | HTT (0.53) | HSD17B3MEN1KMT2AHTTTSHR | |
| SCHEMBL98958 | 0.93 | HTT (0.53) | HSD17B3MEN1KMT2AHTTTSHR | |
| SCHEMBL599773 | 0.93 | HTT (0.53) | HSD17B3MEN1KMT2AHTTTSHR | |
| SCHEMBL2874819 | 0.93 | HTT (0.53) | HSD17B3MEN1KMT2AHTTTSHR | |
| SCHEMBL878501 | 0.93 | HTT (0.53) | HSD17B3MEN1KMT2AHTTTSHR | |
| SCHEMBL98358 | 0.93 | HTT (0.53) | HSD17B3MEN1KMT2AHTTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024062089-A1 | PCSK9 INHIBITORS AND METHODS OF USE THEREOF | ASTRAZENECA AB (SE) | 2024-03-28 | — | — | WO | disclosed |
| WO-2024062090-A1 | PCSK9 INHIBITORS AND METHODS OF USE THEREOF | ASTRAZENECA AB (SE) | 2024-03-28 | — | — | WO | disclosed |
| US-20160324826-A1 | METHOD FOR PROVIDING AN INCREASED EXPRESSION OF TELOMERASE, BRAIN-DERIVED NEUROTROPHIC FACTOR, STROMAL CELL-DERIVED FACTOR-1, CXC CHEMOKINE RECEPTOR 4, AND/OR IMMUNE REGULATORY FACTOR OF STEM CELL | HAWKING BIOLOGICAL TECHNOLOGY CO., LTD. (TW) | 2016-11-10 | — | — | US | disclosed |
| US-20140271568-A1 | METHOD AND KIT FOR PROVIDING AN INCREASED EXPRESSION OF TELOMERASE, BRAIN-DERIVED NEUROTROPHIC FACTOR, STROMAL CELL-DERIVED FACTOR-1, CXC CHEMOKINE RECEPTOR 4, AND/OR IMMUNE REGULATORY FACTOR OF STEM CELL | Hawking Biological Technology Co., Ltd (TW) | 2014-09-18 | — | — | US | disclosed |
| US-8729026-B2 | Method for inhibiting autophagy of motor neurons | CHINA MEDICAL UNIVERSITY (TW) | 2014-05-20 | — | — | US | disclosed |
| US-20140045765-A1 | METHOD FOR INHIBITING AUTOPHAGY OF MOTOR NEURONS | CHINA MEDICAL UNIVERSITY (TW) | 2014-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140271568-A1 | METHOD AND KIT FOR PROVIDING AN INCREASED EXPRESSION OF TELOMERASE, BRAIN-DERIVED NEUROTROPHIC FACTOR, STROMAL CELL-DERIVED FACTOR-1, CXC CHEMOKINE RECEPTOR 4, AND/OR IMMUNE REGULATORY FACTOR OF STEM CELL | CXCL12, CXCR4, BDNF | GABRA1 1550/4885GABRB2 1472/4885HSD17B3 3730/4885 |
| US-20160324826-A1 | METHOD FOR PROVIDING AN INCREASED EXPRESSION OF TELOMERASE, BRAIN-DERIVED NEUROTROPHIC FACTOR, STROMAL CELL-DERIVED FACTOR-1, CXC CHEMOKINE RECEPTOR 4, AND/OR IMMUNE REGULATORY FACTOR OF STEM CELL | CXCL12, CXCR4, BDNF | GABRA1 1270/4885GABRB2 1075/4885HSD17B3 3420/4885 |
| US-20140045765-A1 | METHOD FOR INHIBITING AUTOPHAGY OF MOTOR NEURONS | ATG7, BECN1, SQSTM1 | GABRA1 737/4885GABRB2 163/4885HSD17B3 1886/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.