SCHEMBL154708

SCHEMBL154708

Brc1ccc2c(c1)OCO2

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.65
MAPT P10636 1/20 0.65
HTT P42858 1/20 0.65
BLM P54132 1/20 0.65
MAOB P27338 2/20 0.56
AHR P35869 3/20 0.54
CYP3A4 P08684 2/20 0.54
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
NPC1 O15118 1/20 0.50
CASP3 P42574 1/20 0.50
RAB9A P51151 1/20 0.50
SENP7 Q9BQF6 1/20 0.50
MAOA P21397 1/20 0.49
ALDH1A1 P00352 2/20 0.48
HSD17B10 Q99714 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
ABCG2 Q9UNQ0 1/20 0.48
MAPK1 P28482 1/20 0.47
HSP90AA1 P07900 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29459415 1.00 LMNA (0.65) LMNAMAPTHTTBLMMAOB
SCHEMBL1136696 0.98 MAPT (0.63) LMNAMAPTHTTBLMMAOB
SCHEMBL30304403 0.98 MAPT (0.63) LMNAMAPTHTTBLMMAOB
Methyl Alcohol SCHEMBL28062203 0.93 MAPT (0.59) LMNAMAPTHTTBLMMAOB
SCHEMBL20741831 0.86 LMNA (0.61) LMNAMAPTHTTBLMMAOB
SCHEMBL661042 0.85 MAPT (0.87) LMNAMAPTHTTBLMMAOB
Phenol SCHEMBL27725353 0.84 CYP3A4 (0.55) LMNAMAPTHTTBLMMAOB
SCHEMBL9037655 0.83 MAPT (0.83) LMNAMAPTHTTBLMMAOB
SCHEMBL7759290 0.82 CA12 (0.56) LMNAMAPTHTTBLMMAOB
SCHEMBL21272951 0.81 BLM (0.61) LMNAMAPTHTTBLMMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1344 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4551680-A2 METHODS OF MANUFACTURE OF R-MDMA Mind Medicine, Inc. (US) 2025-05-14 EP claimed
CN-119998433-A Method for producing R-MDMA 思维医学股份有限公司 2025-05-13 CN claimed
CN-116041153-B Direct cross coupling method of aryl thioether and aryl bromine 南京工业大学 2024-05-24 CN claimed
CN-116253623-B Direct cross-coupling method of aryl fluorine sulfate and aryl bromine 南京工业大学 2024-04-05 CN claimed
CN-113527270-B Medical intermediate of PROTAC molecule targeting monoacylglycerol lipase, preparation method and application 河南大学 2024-03-01 CN claimed
WO-2024011067-A2 METHODS OF MANUFACTURE OF R-MDMA Mind Medicine, Inc. (US) 2024-01-11 WO claimed
US-20240010628-A1 METHODS OF MANUFACTURE OF R-MDMA Mind Medicine, Inc. (US) 2024-01-11 US claimed
CN-114591128-B Direct cross-coupling method of aryl sulfide salt and aryl bromide 南京工业大学 2023-08-22 CN claimed
CN-116573994-A Direct cross-coupling method of triazine ester and aryl bromide 南京工业大学 2023-08-11 CN claimed
CN-116554009-A Electrophilic cross-coupling reaction method of aryl sulfone or heteroaryl sulfone and aryl bromide 南京工业大学 2023-08-08 CN claimed
CN-113999263-A Synthesis method of tri-substituted phosphine oxide compound 苏州欣诺科生物科技有限公司 2022-02-01 CN claimed
CN-215538600-U Extraction tank for producing 4-bromo-1, 2-methylenedioxybenzene 苏州兴华高新材料科技有限公司 2022-01-18 CN claimed
CN-113527270-A Medicine intermediate of PROTAC molecule of targeted monoacylglycerol lipase, preparation method and application 河南大学 2021-10-22 CN claimed
CN-113480513-A Preparation method of ilexlyamine 北京斯利安健康科技有限公司 2021-10-08 CN claimed
CN-110724047-B Method for preparing aromatic carboxylic acid compound 中国科学院大连化学物理研究所 2020-10-30 CN claimed
CN-110724047-A Method for preparing aromatic carboxylic acid compound 中国科学院大连化学物理研究所 2020-01-24 CN claimed
CN-102329199-B Method for synthesizing biphenyl compounds under composite catalytic actions of Pd/C and crown ether UNIV HEILONGJIANG 2014-04-02 CN claimed
CN-101243030-B Method for producing 4-halocatechol compound UBE INDUSTRIES, LTD. (JP) 2012-02-01 CN claimed
CN-101243030-A Method for producing 4-halocatechol compound UBE INDUSTRIES (JP) 2008-08-13 CN claimed
US-4605749-A R)ACTING AN ORGANIC HALIDE WITH CARBON MONOXIDE USING A TRAN>ITION METAL CATALYST, A HYDROGEN DONOR, AND A BASE AT LOW PRESSURE STATE OF ISRAEL, PRIME MINISTER'S OFFICE, ATOMIC ENERGY COMMISSION (IL) 1986-08-12 US claimed