Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | BLM | P54132 | 1/20 | 0.63 |
| ▸ | MAOB | P27338 | 2/20 | 0.55 |
| ▸ | AHR | P35869 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL154708 | 0.98 | LMNA (0.65) | MAPTLMNAHTTBLMMAOB | |
| SCHEMBL29459415 | 0.98 | LMNA (0.65) | MAPTLMNAHTTBLMMAOB | |
| SCHEMBL1136696 | 0.95 | MAPT (0.63) | MAPTLMNAHTTBLMMAOB | |
| Methyl Alcohol SCHEMBL28062203 | 0.91 | MAPT (0.59) | MAPTLMNAHTTBLMMAOB | |
| SCHEMBL20741831 | 0.84 | LMNA (0.61) | MAPTLMNAHTTBLMMAOB | |
| SCHEMBL661042 | 0.83 | MAPT (0.87) | MAPTLMNAHTTBLMMAOB | |
| Phenol SCHEMBL27725353 | 0.82 | CYP3A4 (0.55) | MAPTLMNAHTTBLMMAOB | |
| SCHEMBL9037655 | 0.81 | MAPT (0.83) | MAPTLMNAHTTBLMMAOB | |
| SCHEMBL7759290 | 0.80 | CA12 (0.56) | MAPTLMNAHTTBLMMAOB | |
| SCHEMBL21272951 | 0.79 | BLM (0.61) | MAPTLMNAHTTBLMMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025096895-A1 | CARBAMOTHIOATE, AND CARBAMODITHIOATE DERIVATIVES OF MDMA, MDA OR ITS OPTICALLY ACTIVE ( R)- OR ( S)-MDMA AND MDA ISOMERS | EMPATHBIO, INC. (US) | 2025-05-08 | — | — | WO | disclosed |
| EP-4408832-A1 | NOVEL PRODRUGS OF MDMA, MDA, AND DERIVATIVES THEREOF | Empathibio, Inc. (US) | 2024-08-07 | — | — | EP | disclosed |
| WO-2023056102-A1 | NOVEL PRODRUGS OF MDMA, MDA, AND DERIVATIVES THEREOF | ATAI Life Sciences AG (DE) | 2023-04-06 | — | — | WO | disclosed |