Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
| ▸ | KIF11 | P52732 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | PTPRC | P08575 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | SRC | P12931 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2692579 | 0.83 | CA12 (0.59) | CA12CA2CA9KIF11MEN1 | |
| SCHEMBL29459415 | 0.82 | LMNA (0.65) | MAOBMEN1KMT2ANPC1RAB9A | |
| SCHEMBL22162812 | 0.82 | CA12 (0.58) | CA12CA2CA9KIF11MEN1 | |
| SCHEMBL154708 | 0.82 | LMNA (0.65) | MAOBMEN1KMT2ANPC1RAB9A | |
| SCHEMBL404584 | 0.81 | PTGS2 (0.66) | CA12CA2CA9KIF11MEN1 | |
| SCHEMBL30009937 | 0.81 | PTGS2 (0.66) | CA12CA2CA9KIF11MEN1 | |
| SCHEMBL1136696 | 0.80 | MAPT (0.63) | MAOBMEN1KMT2ANPC1RAB9A | |
| SCHEMBL30304403 | 0.80 | MAPT (0.63) | MAOBMEN1KMT2ANPC1RAB9A | |
| SCHEMBL14451001 | 0.79 | CA12 (0.56) | CA12CA2CA9KIF11MEN1 | |
| SCHEMBL3901839 | 0.79 | CA12 (0.61) | CA12CA2CA9KIF11MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0674635-B1 | QUINUCLIDINE DERIVATIVES AS SQUALENE SYNTHASE INHIBITORS | SYNGENTA LTD (GB) | 2001-03-28 | — | — | EP | disclosed |
| EP-0674635-A1 | QUINUCLIDINE DERIVATIVES AS SQUALENE SYNTHASE INHIBITORS | ZENECA LIMITED (GB) | 1995-10-04 | — | — | EP | disclosed |
| WO-1994014803-A1 | QUINUCLIDINE DERIVATIVES AS SQUALENE SYNTHASE INHIBITORS | ZENECA LIMITED (GB) | 1994-07-07 | — | — | WO | disclosed |