Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 8/20 | 0.44 |
| ▸ | MDM2 | Q00987 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | S100A4 | P26447 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10250497 | 0.82 | PDK2 (0.45) | PDK2MDM2SMN1; SMN2HTTLMNA | |
| SCHEMBL15470843 | 0.81 | PDK2 (0.46) | PDK2MDM2SMN1; SMN2HTTLMNA | |
| SCHEMBL13185320 | 0.81 | PDK2 (0.48) | PDK2MDM2SMN1; SMN2NPSR1CHRM5 | |
| SCHEMBL13165953 | 0.79 | PDK2 (0.51) | PDK2MDM2SMN1; SMN2LMNANPSR1 | |
| SCHEMBL26025171 | 0.75 | LMNA (0.42) | PDK2SMN1; SMN2LMNANPSR1ELANE | |
| SCHEMBL24279299 | 0.74 | PDK2 (0.53) | PDK2SMN1; SMN2LMNANPSR1KMT2A | |
| SCHEMBL20121806 | 0.74 | PDK2 (0.49) | PDK2LMNANPSR1ESR1ESR2 | |
| SCHEMBL20618646 | 0.71 | PDK2 (0.42) | PDK2ESR1ESR2ELANEAKR1A1 | |
| SCHEMBL304931 | 0.70 | CFTR (0.42) | PDK2SMN1; SMN2LMNANPSR1KMT2A | |
| SCHEMBL29769743 | 0.70 | CFTR (0.42) | PDK2SMN1; SMN2LMNANPSR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9029504-B2 | Fluorene compound | AJINOMOTO CO., INC. (JP) | 2015-05-12 | — | — | US | disclosed |
| US-20140046022-A1 | FLUORENE COMPOUND | AJINOMOTO CO., INC. (JP) | 2014-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140046022-A1 | FLUORENE COMPOUND | NPPA, FURIN, SFPQ | PDK2 3174/4885MDM2 150/4885SMN1; SMN2 176/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.