Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 7/20 | 0.46 |
| ▸ | MDM2 | Q00987 | 3/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | S100A4 | P26447 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19054950 | 0.88 | PDK2 (0.50) | PDK2ESR1ESR2ELANELMNA | |
| SCHEMBL29117194 | 0.86 | SLC6A3 (0.44) | PDK2MDM2SLC6A3SMN1; SMN2LMNA | |
| SCHEMBL13165981 | 0.83 | PDK2 (0.46) | PDK2MDM2SLC6A3ESR1ESR2 | |
| SCHEMBL23024878 | 0.81 | PDK2 (0.50) | PDK2PGRAKR1A1AKR1B1S100A4 | |
| SCHEMBL13165953 | 0.81 | PDK2 (0.51) | PDK2MDM2SLC6A3ESR1ESR2 | |
| SCHEMBL15470823 | 0.81 | PDK2 (0.44) | PDK2MDM2SLC6A3ESR1ESR2 | |
| SCHEMBL13185530 | 0.80 | PDK2 (0.50) | PDK2SLC6A3SMN1; SMN2CHRM5KMT2A | |
| SCHEMBL15552689 | 0.79 | PDK2 (0.45) | PDK2MDM2ESR1ESR2ELANE | |
| SCHEMBL20121806 | 0.77 | PDK2 (0.49) | PDK2ESR1ESR2ELANELMNA | |
| SCHEMBL25125678 | 0.75 | CYP2A6 (0.47) | PDK2SLC6A3LMNAAKR1A1AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9029504-B2 | Fluorene compound | AJINOMOTO CO., INC. (JP) | 2015-05-12 | — | — | US | disclosed |
| US-20140046022-A1 | FLUORENE COMPOUND | AJINOMOTO CO., INC. (JP) | 2014-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140046022-A1 | FLUORENE COMPOUND | NPPA, FURIN, SFPQ | PDK2 3174/4885MDM2 150/4885SLC6A3 4073/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.