Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFB | P00751 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1447192 | 1.00 | CFB (0.36) | CFBNR1H2NR1H3SMN1; SMN2CYP3A4 | |
| Methoxymethane SCHEMBL3450929 | 0.89 | NR1H2 (0.40) | CFBNR1H2NR1H3SMN1; SMN2CYP3A4 | |
| SCHEMBL29908655 | 0.89 | CFB (0.39) | CFBNR1H2NR1H3SMN1; SMN2CYP3A4 | |
| SCHEMBL606913 | 0.89 | CFB (0.39) | CFBNR1H2NR1H3SMN1; SMN2CYP3A4 | |
| SCHEMBL246216 | 0.89 | CFB (0.39) | CFBNR1H2NR1H3SMN1; SMN2CYP3A4 | |
| SCHEMBL606912 | 0.89 | CFB (0.39) | CFBNR1H2NR1H3SMN1; SMN2CYP3A4 | |
| SCHEMBL27866641 | 0.87 | CFB (0.38) | CFBNR1H2NR1H3SMN1; SMN2CYP3A4 | |
| Hydrochloric Acid SCHEMBL28274724 | 0.87 | CFB (0.38) | CFBNR1H2NR1H3SMN1; SMN2CYP3A4 | |
| Hydrochloric Acid SCHEMBL8207460 | 0.87 | CFB (0.38) | CFBNR1H2NR1H3SMN1; SMN2CYP3A4 | |
| SCHEMBL28282470 | 0.87 | CFB (0.38) | CFBNR1H2NR1H3SMN1; SMN2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102838526-B | Preparation method of chiral Beta-indolyl-Gamma-aldehyde group nitro alkanes | UNIV SOOCHOW | 2015-04-08 | — | — | CN | claimed |
| CN-102838526-A | Preparation method of chiral Beta-indolyl-Gamma-aldehyde group nitro alkanes | UNIV SOOCHOW | 2012-12-26 | — | — | CN | claimed |
| CN-101863815-A | Synthesis method of cis 3-phenyl substituted s-proline derivative | JIAXING EPOCHEM PHARMTECH CO LTD | 2010-10-20 | — | — | CN | claimed |
| CN-110498808-B | Intermediate for synthesizing (2S,3R) -3-substituted phenyl pyrrolidine-2-carboxylic acid and preparation method and application thereof | 浙江晖石药业有限公司 | 2021-11-05 | — | — | CN | disclosed |
| CN-110498808-A | A kind of intermediate and its preparation method and application synthesizing (2S, 3R) -3- substituted-phenyl pyrrolidines -2- carboxylic acid | ZHEJIANG HUISHI PHARMACEUTICAL CO LTD | 2019-11-26 | — | — | CN | disclosed |
| EP-2703381-B1 | METHOD FOR PRODUCING FIVE-MEMBERED RING-CONTAINING COMPOUND | ONO PHARMACEUTICAL CO (JP) | 2015-10-21 | — | — | EP | disclosed |
| CN-102838526-B | Preparation method of chiral Beta-indolyl-Gamma-aldehyde group nitro alkanes | UNIV SOOCHOW | 2015-04-08 | — | — | CN | disclosed |
| CN-102838526-B | Preparation method of chiral Beta-indolyl-Gamma-aldehyde group nitro alkanes | UNIV SOOCHOW | 2015-04-08 | — | — | CN | disclosed |
| US-8716500-B2 | Method for producing five-membered ring-containing compound | ONO PHARMACEUTICAL CO., LTD. (JP) | 2014-05-06 | — | — | US | disclosed |
| EP-2703381-A1 | METHOD FOR PRODUCING FIVE-MEMBERED RING-CONTAINING COMPOUND | Ono Pharmaceutical Co., Ltd. (JP) | 2014-03-05 | — | — | EP | disclosed |
| US-20140051874-A1 | METHOD FOR PRODUCING FIVE-MEMBERED RING-CONTAINING COMPOUND | ONO PHARMACEUTICAL CO., LTD. (JP) | 2014-02-20 | — | — | US | disclosed |
| CN-101914051-B | Synthesis method of 3-phenyl pyrroline derivatives with optical isomerism purity | JIAXING EPOCHEM PHARMTECH CO LTD | 2013-03-13 | — | — | CN | disclosed |
| CN-102838526-A | Preparation method of chiral Beta-indolyl-Gamma-aldehyde group nitro alkanes | UNIV SOOCHOW | 2012-12-26 | — | — | CN | disclosed |
| CN-102838526-A | Preparation method of chiral Beta-indolyl-Gamma-aldehyde group nitro alkanes | UNIV SOOCHOW | 2012-12-26 | — | — | CN | disclosed |
| CN-101914051-A | Synthesis method of 3-phenyl pyrroline derivatives with optical isomerism purity | JIAXING EPOCHEM PHARMTECH CO LTD | 2010-12-15 | — | — | CN | disclosed |
| CN-101863815-A | Synthesis method of cis 3-phenyl substituted s-proline derivative | JIAXING EPOCHEM PHARMTECH CO LTD | 2010-10-20 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140051874-A1 | METHOD FOR PRODUCING FIVE-MEMBERED RING-CONTAINING COMPOUND | PTGIS, ALOX5, PTGES | CFB 3033/4885NR1H2 280/4885NR1H3 405/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.