Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC1 | P33527 | 8/20 | 0.94 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.94 |
| ▸ | MAPT | P10636 | 2/20 | 0.94 |
| ▸ | GMNN | O75496 | 1/20 | 0.94 |
| ▸ | LMNA | P02545 | 1/20 | 0.94 |
| ▸ | TP53 | P04637 | 1/20 | 0.94 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.94 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.94 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.94 |
| ▸ | TSHR | P16473 | 1/20 | 0.94 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.94 |
| ▸ | THPO | P40225 | 1/20 | 0.94 |
| ▸ | BLM | P54132 | 1/20 | 0.94 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.94 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.94 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.94 |
| ▸ | GSR | P00390 | 3/20 | 0.67 |
| ▸ | ABCB1 | P08183 | 5/20 | 0.51 |
| ▸ | CA12 | O43570 | 4/20 | 0.48 |
| ▸ | CA1 | P00915 | 4/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Furoxan SCHEMBL320190 | 0.97 | ABCC1 (1.00) | ABCC1ALDH1A1MAPTGMNNLMNA | |
| SCHEMBL1547974 | 0.92 | ABCC1 (0.83) | ABCC1ALDH1A1MAPTGMNNLMNA | |
| SCHEMBL1547730 | 0.85 | GSR (0.81) | ABCC1ALDH1A1MAPTGMNNLMNA | |
| SCHEMBL1548118 | 0.84 | ABCC1 (0.71) | ABCC1ALDH1A1MAPTGMNNLMNA | |
| SCHEMBL1547817 | 0.84 | ABCC1 (0.71) | ABCC1ALDH1A1MAPTGMNNLMNA | |
| SCHEMBL1547962 | 0.84 | ABCC1 (0.71) | ABCC1ALDH1A1MAPTGMNNLMNA | |
| SCHEMBL1547742 | 0.84 | ABCC1 (0.71) | ABCC1ALDH1A1MAPTGMNNLMNA | |
| SCHEMBL1547686 | 0.84 | ABCC1 (0.71) | ABCC1ALDH1A1MAPTGMNNLMNA | |
| SCHEMBL1548166 | 0.82 | ABCC1 (0.68) | ABCC1ALDH1A1MAPTGMNNLMNA | |
| SCHEMBL1548148 | 0.80 | ALDH1A1 (0.66) | ABCC1ALDH1A1MAPTGMNNLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110207784-A1 | OXADIAZOLE-2-OXIDES AS ANTISCHISTOSOMAL AGENTS | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, | 2011-08-25 | — | — | US | claimed |
| EP-2310378-A2 | OXADIAZOLE-2-OXIDES AS ANTISCHISTOSOMAL AGENTS | The U.S.A. As Represented By The Secretary, Department Of Health And Human Services (US) | 2011-04-20 | — | — | EP | claimed |
| WO-2010019772-A2 | OXADIAZOLE-2-OXIDES AS ANTISCHISTOSOMAL AGENTS | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2010-02-18 | — | — | WO | claimed |
| US-20110207784-A1 | OXADIAZOLE-2-OXIDES AS ANTISCHISTOSOMAL AGENTS | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, | 2011-08-25 | — | — | US | disclosed |
| EP-2310378-A2 | OXADIAZOLE-2-OXIDES AS ANTISCHISTOSOMAL AGENTS | The U.S.A. As Represented By The Secretary, Department Of Health And Human Services (US) | 2011-04-20 | — | — | EP | disclosed |
| WO-2010019772-A2 | OXADIAZOLE-2-OXIDES AS ANTISCHISTOSOMAL AGENTS | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2010-02-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110207784-A1 | OXADIAZOLE-2-OXIDES AS ANTISCHISTOSOMAL AGENTS | ARG2, OXA1L, SQOR | ABCC1 201/4885ALDH1A1 251/4885MAPT 4497/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.