SCHEMBL1547546

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1548031	0.95	POLB (0.40)	MAPK14MAPK11STAT3STAT1KIT
	SCHEMBL1547885	0.94	TP53 (0.38)	HTTKITPOLBMAPTADCY8
	SCHEMBL1547998	0.93	ADCY1 (0.39)	MAPK14MAPK11KITADCY8ADCY1
	SCHEMBL1547375	0.92	KMT2A (0.39)	MAPK14MAPK11KITPOLBMAPT
	SCHEMBL1547953	0.92	ALDH1A1 (0.41)	BRAFKITPOLBACLYMAPT
	SCHEMBL1548038	0.91	KDM4E (0.41)	MAPK14MAPK11KITPOLBMAPT
	SCHEMBL1547830	0.91	MAPT (0.43)	MAPK14HTTMAPTADCY1ABCG2
	SCHEMBL1575971	0.91	MEN1 (0.39)	MAPK14MAPK11KITADCY8ADCY1
	SCHEMBL1547616	0.91	HDAC1 (0.39)	BRAFMAPK14KITACLYMAPT
	SCHEMBL13318864	0.91	LDLR (0.40)	MAPK14MAPK11KITPOLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.