SCHEMBL15475475

SCHEMBL15475475

C=C(Cc1ccccc1)C(=O)OC12CCC(CC1)C2

nearest known ligand 0.37

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 2/20 0.37
CYP17A1 P05093 1/20 0.37
ALDH1A1 P00352 4/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
EPHX2 P34913 2/20 0.35
P2RX7 Q99572 2/20 0.35
CES2 O00748 1/20 0.35
CES1 P23141 1/20 0.35
AKR1B1 P15121 1/20 0.35
L3MBTL1 Q9Y468 2/20 0.34
HPGD P15428 2/20 0.34
GLA P06280 1/20 0.34
OPRM1 P35372 1/20 0.34
OPRL1 P41146 1/20 0.34
MAPK1 P28482 1/20 0.33
HSD11B1 P28845 1/20 0.33
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28582716 0.70 CES1 (0.52) ALDH1A1MEN1KMT2AEPHX2CES2
SCHEMBL2965753 0.70
SCHEMBL24944055 0.70 OPRM1 (0.46) ALDH1A1MEN1KMT2ACES2CES1
SCHEMBL6410147 0.70 AKR1C3 (0.45) ALDH1A1MEN1KMT2AHPGDMAPK1
SCHEMBL7693742 0.70 CYP19A1 (0.49) CYP19A1ALDH1A1MEN1KMT2ACES2
SCHEMBL448851 0.70 ALDH1A1 (0.35) ALDH1A1
SCHEMBL8767243 0.69 CES1 (0.50) ALDH1A1MEN1KMT2AEPHX2CES2
Methacrylic Acid SCHEMBL4802536 0.69 ALDH1A1 (0.32) ALDH1A1
SCHEMBL28576628 0.69 CYP19A1 (0.49) CYP19A1ALDH1A1MEN1KMT2AEPHX2
SCHEMBL1702939 0.68 ABCG2 (0.39) MEN1KMT2AHPGDLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140049728-A1 LIGHT GUIDE PLATE, LIGHT-EMITTING UNIT AND LIQUID CRYSTAL DISPLAY DEVICE HAVING THE SAME CHI MEI CORPORATION (TW) 2014-02-20 US disclosed