SCHEMBL15475586

SCHEMBL15475586

O=C(O)CCC(=O)OCCCC1OCCN(c2ccc(N3C[C@H](CNC(=O)c4ccc(Cl)s4)OC3=O)cc2)C1=O

nearest known ligand 0.60

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
F10 P00742 20/20 0.60
F2 P00734 5/20 0.58
ABCB11 O95342 1/20 0.58
ST14 Q9Y5Y6 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11890743 0.92 F10 (0.58) F10F2ABCB11ST14
SCHEMBL15482067 0.91 F10 (0.60) F10
SCHEMBL15475575 0.86 F10 (0.69) F10F2ABCB11ST14
SCHEMBL11890681 0.84 F10 (0.58) F10
SCHEMBL11890751 0.84 F10 (0.66) F10F2ABCB11ST14
SCHEMBL15475850 0.82 F10 (0.46) F10F2ABCB11ST14
SCHEMBL11890685 0.80 F10 (0.69) F10F2ABCB11ST14
SCHEMBL28404065 0.80 F10 (0.76) F10F2ABCB11ST14
SCHEMBL15475736 0.78 F10 (0.68) F10
SCHEMBL11890741 0.76 F10 (0.65) F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140050743-A1 BINDING PROTEINS TO INHIBITORS OF COAGULATION FACTORS BAYER INTELLECTUAL PROPERTY GMBH (DE) 2014-02-20 US disclosed
US-20140050743-A1 BINDING PROTEINS TO INHIBITORS OF COAGULATION FACTORS BAYER INTELLECTUAL PROPERTY GMBH (DE) 2014-02-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140050743-A1 BINDING PROTEINS TO INHIBITORS OF COAGULATION FACTORS F13B, F11, SERPINC1 F10 10/4885F2 8/4885ABCB11 3023/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.