Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.36 |
| ▸ | CCR1 | P32246 | 3/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15478335 | 0.88 | DRD2 (0.34) | DRD2CCR1OPRM1OPRL1SIGMAR1 | |
| SCHEMBL15478333 | 0.85 | DRD2 (0.40) | DRD2CCR1OPRM1OPRL1DRD4 | |
| SCHEMBL15478355 | 0.83 | CCR1 (0.38) | DRD2CCR1OPRM1OPRL1SIGMAR1 | |
| SCHEMBL15478402 | 0.83 | DRD2 (0.34) | DRD2CCR1OPRM1OPRL1SIGMAR1 | |
| SCHEMBL15478359 | 0.83 | CCR1 (0.38) | DRD2CCR1OPRM1OPRL1DRD4 | |
| SCHEMBL15478375 | 0.83 | CCR1 (0.50) | DRD2CCR1OPRM1OPRL1SIGMAR1 | |
| SCHEMBL18895953 | 0.82 | LMNA (0.39) | ALDH1A1LMNA | |
| SCHEMBL15478400 | 0.81 | CCR1 (0.37) | DRD2CCR1OPRM1SIGMAR1DRD4 | |
| SCHEMBL14419960 | 0.80 | DRD2 (0.37) | DRD2CCR1OPRM1OPRL1SIGMAR1 | |
| SCHEMBL15478401 | 0.80 | CCR1 (0.37) | DRD2CCR1OPRM1OPRL1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8653096-B2 | Chemokine receptor antagonists and methods of use thereof | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2014-02-18 | — | — | US | disclosed |