SCHEMBL15479214

SCHEMBL15479214

O=P(c1ccccc1)(c1ccccc1)c1ccc(-c2ccc(-c3ccc4c5ccccc5c5nc6ccccc6n5c4c3)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 7/20 0.50
KDM4E B2RXH2 7/20 0.50
ALDH1A1 P00352 6/20 0.50
KMT2A Q03164 6/20 0.48
SMN1; SMN2 Q16637 3/20 0.48
MAPT P10636 5/20 0.45
POLB P06746 4/20 0.45
HSD17B10 Q99714 3/20 0.45
LMNA P02545 2/20 0.45
TP53 P04637 1/20 0.45
MEN1 O00255 4/20 0.42
CAMKK1 Q8N5S9 2/20 0.40
CAMKK2 Q96RR4 2/20 0.40
CYP1A2 P05177 2/20 0.40
CYP2D6 P10635 1/20 0.40
CYP2C9 P11712 1/20 0.40
CASP1 P29466 1/20 0.40
CYP2C19 P33261 1/20 0.40
CASP7 P55210 1/20 0.40
BCL2 P10415 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15479209 1.00 HPGD (0.50) HPGDKDM4EALDH1A1KMT2ASMN1; SMN2
SCHEMBL15479243 0.96 ALDH1A1 (0.50) HPGDKDM4EALDH1A1KMT2ASMN1; SMN2
SCHEMBL15479268 0.96 ALDH1A1 (0.46) HPGDKDM4EALDH1A1KMT2ASMN1; SMN2
SCHEMBL15479264 0.95 ALDH1A1 (0.47) HPGDKDM4EALDH1A1KMT2ASMN1; SMN2
SCHEMBL15479210 0.94 KDM4E (0.45) HPGDKDM4EALDH1A1KMT2ASMN1; SMN2
SCHEMBL15479213 0.94 KDM4E (0.45) HPGDKDM4EALDH1A1KMT2ASMN1; SMN2
SCHEMBL15479274 0.94 KDM4E (0.47) HPGDKDM4EALDH1A1KMT2ASMN1; SMN2
SCHEMBL15479203 0.94 KDM4E (0.46) HPGDKDM4EALDH1A1KMT2ASMN1; SMN2
SCHEMBL15479205 0.94 KDM4E (0.46) HPGDKDM4EALDH1A1KMT2ASMN1; SMN2
SCHEMBL19928980 0.94 KDM4E (0.48) HPGDKDM4EALDH1A1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11362280-B2 Organic light-emitting device LG CHEM, LTD. (KR) 2022-06-14 US disclosed
US-11342508-B2 Organic light-emitting device LG CHEM, LTD. (KR) 2022-05-24 US disclosed
EP-2750214-B1 ORGANIC LIGHT-EMITTING DEVICE AND METHOD FOR MANUFACTURING SAME LG CHEMICAL LTD (KR) 2020-06-17 EP disclosed
US-20180175302-A1 ORGANIC LIGHT-EMITTING DEVICE LG CHEM, LTD. (KR) 2018-06-21 US disclosed
US-20180175302-A1 ORGANIC LIGHT-EMITTING DEVICE LG CHEM, LTD. (KR) 2018-06-21 US disclosed
US-9972784-B2 Compounds and organic electronic device using same LG CHEM, LTD. (KR) 2018-05-15 US disclosed
US-9972784-B2 Compounds and organic electronic device using same LG CHEM, LTD. (KR) 2018-05-15 US disclosed
US-9887368-B2 Organic light-emitting device and method for manufacturing same LG CHEM, LTD. (KR) 2018-02-06 US disclosed
US-9887368-B2 Organic light-emitting device and method for manufacturing same LG CHEM, LTD. (KR) 2018-02-06 US disclosed
EP-2719742-B1 NOVEL COMPOUNDS AND ORGANIC ELECTRONIC DEVICE USING SAME LG CHEMICAL LTD (KR) 2016-04-27 EP disclosed
US-20140110694-A1 NOVEL COMPOUNDS AND ORGANIC ELECTRONIC DEVICE USING SAME LG CHEM, LTD. (KR) 2014-04-24 US disclosed
US-20140110694-A1 NOVEL COMPOUNDS AND ORGANIC ELECTRONIC DEVICE USING SAME LG CHEM, LTD. (KR) 2014-04-24 US disclosed
US-20140048792-A1 ORGANIC LIGHT-EMITTING DEVICE AND METHOD FOR MANUFACTURING SAME LG CHEM, LTD. (KR) 2014-02-20 US disclosed
US-20140048792-A1 ORGANIC LIGHT-EMITTING DEVICE AND METHOD FOR MANUFACTURING SAME LG CHEM, LTD. (KR) 2014-02-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11342508-B2 Organic light-emitting device CRY1, CRY2, NR2E3 HPGD 3262/4885KDM4E 2028/4885ALDH1A1 103/4885
US-20180175302-A1 ORGANIC LIGHT-EMITTING DEVICE CRY1, CRY2, NR2E3 HPGD 3262/4885KDM4E 2028/4885ALDH1A1 103/4885
US-11362280-B2 Organic light-emitting device CRY1, CRY2, NR2E3 HPGD 3262/4885KDM4E 2028/4885ALDH1A1 103/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.