SCHEMBL15480385

SCHEMBL15480385

OB(O)c1ccc2c(c1)c1ccccc1n2-c1ccc2c3c(cccc13)-c1ccccc1-2

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CRHBP P24387 1/20 0.34
CRHR2 Q13324 1/20 0.34
KEAP1 Q14145 1/20 0.34
NFE2L2 Q16236 1/20 0.34
L3MBTL1 Q9Y468 3/20 0.33
ALDH1A1 P00352 2/20 0.33
HPGD P15428 1/20 0.33
TSHR P16473 1/20 0.33
MAPK1 P28482 1/20 0.33
CASP1 P29466 1/20 0.33
HIF1A Q16665 1/20 0.33
HSD17B10 Q99714 1/20 0.33
DUSP3 P51452 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
MGLL Q99685 1/20 0.31
IDO1 P14902 1/20 0.31
TDO2 P48775 1/20 0.31
HKDC1 Q2TB90 1/20 0.31
MAPT P10636 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15479798 0.82 CRHBP (0.39) CRHBPCRHR2KEAP1NFE2L2L3MBTL1
SCHEMBL29552193 0.81 CA1 (0.42) L3MBTL1ALDH1A1HPGDTSHRMAPK1
SCHEMBL29888544 0.81 CA1 (0.42) L3MBTL1ALDH1A1HPGDTSHRMAPK1
SCHEMBL3664181 0.81 CA1 (0.42) L3MBTL1ALDH1A1HPGDTSHRMAPK1
SCHEMBL17915579 0.80 CRHBP (0.40) CRHBPCRHR2KEAP1NFE2L2L3MBTL1
SCHEMBL15480384 0.80 TSPO (0.40) CRHBPCRHR2KEAP1NFE2L2L3MBTL1
SCHEMBL17810050 0.80 DUSP3 (0.43) L3MBTL1ALDH1A1DUSP3CA1CA2
SCHEMBL17341510 0.79 CRHBP (0.39) CRHBPCRHR2KEAP1NFE2L2L3MBTL1
SCHEMBL18918054 0.78 ALDH1A1 (0.41) L3MBTL1ALDH1A1HSD17B10DUSP3CA1
SCHEMBL15479801 0.78 CRHBP (0.36) CRHBPCRHR2KEAP1NFE2L2L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160268517-A1 BISCARBAZOLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2016-09-15 US disclosed
US-20160268517-A1 BISCARBAZOLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2016-09-15 US disclosed
US-20150249219-A1 BISCARBAZOLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2015-09-03 US disclosed
US-20150249219-A1 BISCARBAZOLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2015-09-03 US disclosed
US-20140048784-A1 BISCARBAZOLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2014-02-20 US disclosed
US-20140048784-A1 BISCARBAZOLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2014-02-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160268517-A1 BISCARBAZOLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME L1CAM, CCNT1, CCNA1 CRHBP 4299/4885CRHR2 3787/4885KEAP1 2033/4885
US-20150249219-A1 BISCARBAZOLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME L1CAM, CCNT1, CCNA1 CRHBP 4292/4885CRHR2 3792/4885KEAP1 2049/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.