Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.61 |
| ▸ | PKM | P14618 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 4/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.57 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | NQO2 | P16083 | 1/20 | 0.56 |
| ▸ | CASP3 | P42574 | 1/20 | 0.56 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4020377 | 0.85 | MAPT (0.57) | MEN1KMT2AALDH1A1NR1H4NPC1 | |
| SCHEMBL4020386 | 0.85 | MAPT (0.59) | MEN1KMT2AALDH1A1NPC1POLB | |
| SCHEMBL4024552 | 0.84 | NR1H4 (0.53) | MEN1KMT2AALDH1A1NR1H4NPC1 | |
| SCHEMBL15480650 | 0.84 | MEN1 (0.70) | MEN1KMT2APKMALDH1A1NPC1 | |
| SCHEMBL29944952 | 0.83 | ROCK2 (0.66) | MEN1KMT2AALDH1A1NR1H4NPC1 | |
| SCHEMBL4024140 | 0.83 | HDAC1 (0.57) | MEN1KMT2AALDH1A1NR1H4NPC1 | |
| SCHEMBL14490974 | 0.83 | NPC1 (0.69) | MEN1KMT2AALDH1A1NPC1POLB | |
| SCHEMBL4020644 | 0.82 | HDAC1 (0.58) | MAPTLMNASMN1; SMN2HDAC1HDAC6 | |
| SCHEMBL21156696 | 0.80 | EPHX2 (0.64) | KMT2AALDH1A1POLBMAPTLMNA | |
| SCHEMBL4656274 | 0.80 | NPC1 (0.71) | MEN1KMT2AALDH1A1NR1H4NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1874722-B1 | HYDROXAMIC ACID DERIVATIVES AND THE PREPARATION METHOD THEREOF | AMOREPACIFIC CORP (KR) | 2015-04-08 | — | — | EP | claimed |
| US-7485750-B2 | Hydroxamic acid derivatives and the preparation method thereof | AMOREPACIFIC CORPORATION (KR) | 2009-02-03 | — | — | US | claimed |
| US-20080242730-A1 | Hydroxamic Acid Derivatives and the Preparation Method Thereof | AMOREPACIFIC CORPORATION (KR) | 2008-10-02 | — | — | US | claimed |
| EP-1874722-A1 | HYDROXAMIC ACID DERIVATIVES AND THE PREPARATION METHOD THEREOF | Amorepacific Corporation (KR) | 2008-01-09 | — | — | EP | claimed |
| WO-2006118380-A1 | HYDROXAMIC ACID DERIVATIVES AND THE PREPARATION METHOD THEREOF | AMOREPACIFIC CORPORATION (KR) | 2006-11-09 | — | — | WO | claimed |
| EP-1874722-B1 | HYDROXAMIC ACID DERIVATIVES AND THE PREPARATION METHOD THEREOF | AMOREPACIFIC CORP (KR) | 2015-04-08 | — | — | EP | disclosed |
| US-7485750-B2 | Hydroxamic acid derivatives and the preparation method thereof | AMOREPACIFIC CORPORATION (KR) | 2009-02-03 | — | — | US | disclosed |
| US-20080242730-A1 | Hydroxamic Acid Derivatives and the Preparation Method Thereof | AMOREPACIFIC CORPORATION (KR) | 2008-10-02 | — | — | US | disclosed |
| EP-1874722-A1 | HYDROXAMIC ACID DERIVATIVES AND THE PREPARATION METHOD THEREOF | Amorepacific Corporation (KR) | 2008-01-09 | — | — | EP | disclosed |
| WO-2006118380-A1 | HYDROXAMIC ACID DERIVATIVES AND THE PREPARATION METHOD THEREOF | AMOREPACIFIC CORPORATION (KR) | 2006-11-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080242730-A1 | Hydroxamic Acid Derivatives and the Preparation Method Thereof | COL14A1, CUTA, COL2A1 | MEN1 4712/4885KMT2A 1541/4885PKM 2574/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.