Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 9/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 9/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 9/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12756731 | 0.92 | CASP3 (0.39) | PI4KBHDAC3HDAC1HDAC2CASP3 | |
| SCHEMBL12830908 | 0.85 | HDAC1 (0.46) | HDAC3HDAC1HDAC2CASP3SENP8 | |
| SCHEMBL15258591 | 0.81 | CASP3 (0.56) | CASP3SENP8SENP7SENP6KMT2A | |
| SCHEMBL12756734 | 0.79 | NPY5R (0.39) | HDAC3HDAC1HDAC2CASP3SENP8 | |
| SCHEMBL12756748 | 0.77 | P2RX7 (0.41) | HDAC3HDAC1HDAC2CASP3SENP8 | |
| SCHEMBL12756740 | 0.76 | CASP3 (0.43) | HDAC3HDAC1HDAC2CASP3SENP8 | |
| SCHEMBL12756738 | 0.74 | ABL1 (0.56) | HDAC3HDAC1HDAC2KMT2APOLB | |
| SCHEMBL1490559 | 0.73 | MEN1 (0.47) | HDAC2KMT2AMEN1NPC1RAB9A | |
| SCHEMBL12830925 | 0.73 | MEN1 (0.47) | HDAC2KMT2AMEN1NPC1RAB9A | |
| SCHEMBL12830039 | 0.73 | HDAC4 (0.47) | NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140051711-A1 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | CALCIMEDICA INC. (US) | 2014-02-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140051711-A1 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | ORAI1, SARAF, RYR2 | PI4KB 303/4885HDAC3 1653/4885HDAC1 2696/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.