Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 7/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 7/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | STK17B | O94768 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CETP | P11597 | 1/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.41 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.41 |
| ▸ | DAPK2 | Q9UIK4 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15480660 | 0.85 | PI4KB (0.41) | HDAC1HDAC2HDAC3CASP3SENP8 | |
| SCHEMBL12756740 | 0.84 | CASP3 (0.43) | HDAC1HDAC2HDAC3CASP3SENP8 | |
| SCHEMBL12756731 | 0.84 | CASP3 (0.39) | HDAC1HDAC2HDAC3CASP3SENP8 | |
| SCHEMBL12756734 | 0.84 | NPY5R (0.39) | HDAC1HDAC2HDAC3CASP3SENP8 | |
| SCHEMBL12756748 | 0.82 | P2RX7 (0.41) | HDAC1HDAC2HDAC3CASP3SENP8 | |
| SCHEMBL12756666 | 0.77 | HDAC4 (0.47) | HPGDNPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL12830039 | 0.77 | HDAC4 (0.47) | HPGDNPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL1490556 | 0.77 | MEN1 (0.54) | HDAC2CASP3SENP8SENP7SENP6 | |
| SCHEMBL12756743 | 0.77 | HDAC1 (0.52) | HDAC1HDAC2 | |
| SCHEMBL12756738 | 0.76 | ABL1 (0.56) | HDAC1HDAC2HDAC3HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011034962-A2 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | CALCIMEDICA INC. (US) | 2011-03-24 | — | — | WO | disclosed |