SCHEMBL15481663

SCHEMBL15481663

O=[N+]([O-])c1ccccc1-c1ccc2cc(-c3ccccc3)[nH]c2c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.55
TDP1 Q9NUW8 1/20 0.55
CYP19A1 P11511 4/20 0.53
NPC1 O15118 4/20 0.49
MEN1 O00255 4/20 0.49
KMT2A Q03164 4/20 0.49
CASP3 P42574 2/20 0.49
SENP8 Q96LD8 2/20 0.49
SENP7 Q9BQF6 2/20 0.49
SENP6 Q9GZR1 2/20 0.49
POLB P06746 1/20 0.49
RAB9A P51151 3/20 0.47
CDC7 O00311 1/20 0.44
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA9 Q16790 1/20 0.42
GUSB P08236 1/20 0.41
MAPT P10636 3/20 0.40
KDM4E B2RXH2 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15477928 0.89 CYP19A1 (0.64) ALDH1A1TDP1CYP19A1NPC1MEN1
SCHEMBL15596485 0.86 CYP19A1 (0.50) ALDH1A1TDP1CYP19A1NPC1MEN1
SCHEMBL2244487 0.79 CYP19A1 (0.78) CYP19A1NPC1MEN1KMT2ACASP3
SCHEMBL15055251 0.77 ALDH1A1 (0.66) ALDH1A1TDP1NPC1CASP3SENP7
SCHEMBL32674566 0.77 KMT2A (0.56) ALDH1A1TDP1CYP19A1NPC1MEN1
SCHEMBL7107605 0.77 KMT2A (0.56) ALDH1A1TDP1CYP19A1NPC1MEN1
SCHEMBL15477943 0.76 ALDH1A1 (0.51) ALDH1A1TDP1NPC1MEN1KMT2A
SCHEMBL15055905 0.76 ALDH1A1 (0.63) ALDH1A1TDP1MAPTCYP1A2CYP2C9
SCHEMBL5130538 0.76 NPC1 (0.68) ALDH1A1CYP19A1NPC1MEN1KMT2A
SCHEMBL14979389 0.75 ALDH1A1 (0.61) ALDH1A1TDP1NPC1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10038146-B2 Organic light-emitting compound and organic electroluminescent device using same DOOSAN CORPORATION (KR) 2018-07-31 US disclosed
US-10038146-B2 Organic light-emitting compound and organic electroluminescent device using same DOOSAN CORPORATION (KR) 2018-07-31 US disclosed
US-9837618-B2 Compound and organic electroluminescence device including thesame DOOSAN CORPORATION (KR) 2017-12-05 US disclosed
US-9837618-B2 Compound and organic electroluminescence device including thesame DOOSAN CORPORATION (KR) 2017-12-05 US disclosed
US-20150236272-A1 NOVEL COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THESAME DOOSAN CORPORATION (KR) 2015-08-20 US disclosed
US-20150236272-A1 NOVEL COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THESAME DOOSAN CORPORATION (KR) 2015-08-20 US disclosed
WO-2015111942-A2 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME 주식회사 두산 2015-07-30 WO disclosed
CN-104736541-A Novel compound and organic electroluminescent element comprising same DOOSAN CORP 2015-06-24 CN disclosed
US-20140374724-A1 ORGANIC LIGHT-EMITTING COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME DOOSAN CORPORATION (KR) 2014-12-25 US disclosed
WO-2014065498-A1 ORGANIC ELECTROLUMINESCENT DEVICE 주식회사 두산 (KR) 2014-05-01 WO disclosed
WO-2014046392-A1 ORGANIC COMPOUND AND ELECTROLUMINESCENT ELEMENT HAVING SAME 주식회사 두산 (KR) 2014-03-27 WO disclosed
WO-2014046392-A1 ORGANIC COMPOUND AND ELECTROLUMINESCENT ELEMENT HAVING SAME 주식회사 두산 (KR) 2014-03-27 WO disclosed
WO-2014027822-A1 NOVEL COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME 주식회사 두산 (KR) 2014-02-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10038146-B2 Organic light-emitting compound and organic electroluminescent device using same IDO1, IDO2, KYNU ALDH1A1 458/4885TDP1 2908/4885CYP19A1 870/4885
US-20150236272-A1 NOVEL COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THESAME INMT, IDO1, IDO2 ALDH1A1 1188/4885TDP1 2483/4885CYP19A1 1414/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.