Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Diethylpropion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 1.00 |
| ▸ | ADRA2A | P08913 | 1/20 | 1.00 |
| ▸ | ADRA2B | P18089 | 1/20 | 1.00 |
| ▸ | HTR2A | P28223 | 1/20 | 1.00 |
| ▸ | HRH1 | P35367 | 1/20 | 1.00 |
| ▸ | KCNH2 | Q12809 | 1/20 | 1.00 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diethylpropion SCHEMBL27330 | 1.00 | PGR (1.00) | PGRADRA2AADRA2BHTR2AHRH1 | |
| Diethylpropion SCHEMBL15483 | 0.98 | PGR (0.96) | PGRADRA2AADRA2BHTR2AHRH1 | |
| Diethylpropion SCHEMBL506145 | 0.98 | PGR (0.96) | PGRADRA2AADRA2BHTR2AHRH1 | |
| Diethylpropion SCHEMBL7715371 | 0.98 | PGR (0.96) | PGRADRA2AADRA2BHTR2AHRH1 | |
| Diethylpropion SCHEMBL22614735 | 0.98 | PGR (0.96) | PGRADRA2AADRA2BHTR2AHRH1 | |
| Diethylpropion SCHEMBL5546846 | 0.96 | PGR (0.93) | PGRADRA2AADRA2BHTR2AHRH1 | |
| Diethylpropion SCHEMBL18141848 | 0.96 | PGR (0.93) | PGRADRA2AADRA2BHTR2AHRH1 | |
| Diethylpropion SCHEMBL3051269 | 0.96 | PGR (0.93) | PGRADRA2AADRA2BHTR2AHRH1 | |
| Diethylpropion SCHEMBL9101119 | 0.96 | PGR (0.93) | PGRADRA2AADRA2BHTR2AHRH1 | |
| Diethylpropion SCHEMBL5244701 | 0.96 | PGR (0.93) | PGRADRA2AADRA2BHTR2AHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 86404 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260086062-A1 | IMMOBILIZATION STRATEGIES FOR ENHANCING SENSITIVITY OF ELECTROCHEMICAL APTAMER-BASED SENSORS | THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (US) | 2026-03-26 | — | — | US | claimed |
| EP-4654966-A1 | METHODS AND COMPOSITIONS FOR TREATMENT OF OBESITY AND DISEASES ASSOCIATED WITH FAT CELL ENLARGEMENT | MELLICELL, INC. (US) | 2025-12-03 | — | — | EP | claimed |
| WO-2025137653-A1 | METHODS AND COMPOSITIONS OF POLYCYCLIC AND A DUAL ACTING NITROXIDE COMPOUNDS FOR TREATMENT OF FAT CELL ASSOCIATED DISEASES | MELLICELL, INC. (US) | 2025-06-26 | — | — | WO | claimed |
| WO-2024159211-A1 | METHODS AND COMPOSITIONS FOR TREATMENT OF OBESITY AND DISEASES ASSOCIATED WITH FAT CELL ENLARGEMENT | MELLICELL, INC. (US) | 2024-08-02 | — | — | WO | claimed |
| WO-2024149597-A1 | METHOD FOR ADDITIVELY MANUFACTURING A MEDICAL AND/OR PHARMACEUTICAL PRODUCT, AND CORRESPONDING PRODUCT | BLZ Bayerisches Laserzentrum Gemeinnützige Forschungsgesellschaft mbH (DE) | 2024-07-18 | — | — | WO | claimed |
| WO-2024149823-A1 | OPTICAL SYSTEM AND LITHOGRAPHY SYSTEM | CARL ZEISS SMT GMBH (DE) | 2024-07-18 | — | — | WO | claimed |
| WO-2024149839-A1 | METHOD AND DEVICE FOR VACUUM DIE CASTING | NINKEL THOMAS (DE) | 2024-07-18 | — | — | WO | claimed |
| WO-2024149840-A1 | DEVICE FOR METERING MELT TO A DIE CASTING MACHINE | NINKEL THOMAS (DE) | 2024-07-18 | — | — | WO | claimed |
| EP-3705226-B1 | WORKING CENTER PROVIDED WITH AN INTERCHANGEABLE WORKING PLANE AND OPERATION METHOD THEREOF | SCM GROUP SPA (IT) | 2024-07-17 | — | — | EP | claimed |
| EP-3730265-B1 | COOLING ROLL AND METHOD FOR PRODUCING THERMOPLASTIC RESIN SHEET USING SAME | KOKA CHROME IND CO LTD (JP) | 2024-07-17 | — | — | EP | claimed |
| EP-0007034-A1 | Arrangement for measuring the distance between a metallic workpiece and a tool | Precitec Gesellschaft für Präzisionstechnik und Elektronik mbH & Co. (DE) | 1980-01-23 | — | — | EP | claimed |
| EP-0006892-A1 | Encapsulating process of a ceramic piece. | MTU MUENCHEN GMBH (DE) | 1980-01-23 | — | — | EP | claimed |
| EP-0006544-A1 | Implantable material for bone replacement based on calcium phosphate ceramics in a matrix and method of preparing same | Battelle-Institut e.V. (DE) | 1980-01-09 | — | — | EP | claimed |
| EP-0005198-A1 | Process for manufacturing a dense ceramic material with a high purity mullite content | International Business Machines Corporation (US) | 1979-11-14 | — | — | EP | claimed |
| WO-1979000814-A1 | SEMICONDUCTOR DEVICE COMPRISING TWO SEMICONDUCTOR ELEMENTS | BBC BROWN BOVERI & CIE (DE) | 1979-10-18 | — | — | WO | claimed |
| EP-0004405-A2 | Process for the formation of high-purity tetrahydrophthalic acid anhydride | CHEMISCHE WERKE HÜLS AG (DE) | 1979-10-03 | — | — | EP | claimed |
| EP-0002688-A1 | Apparatus for irradiation of a target with ions | International Business Machines Corporation (US) | 1979-07-11 | — | — | EP | claimed |
| EP-0002000-A1 | Gas discharge display device using spacing elements and method for making a spacing element structure and such a display device | SIEMENS AKTIENGESELLSCHAFT (DE) | 1979-05-30 | — | — | EP | claimed |
| WO-1979000101-A1 | ENCAPSULATING PROCESS OF A CERAMIC PIECE | MTU MUENCHEN GMBH (DE) | 1979-03-08 | — | — | WO | claimed |
| US-3964641-A | Device for dispensing flowable materials | ALFRED FISCHBACH KG KUNSTSTOFF-SPRITZGUSSWERK (DT) | 1976-06-22 | — | — | US | claimed |