SCHEMBL15499183

SCHEMBL15499183

CCC(C)(C)Oc1ccc(C(C)c2ccc(OC(=O)c3ccc(Oc4ccc(C(=O)C(C)(C)CC)cc4)cc3)c(C)c2)cc1C

nearest known ligand 0.35

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TAS1R3 Q7RTX0 1/20 0.33
TAS1R1 Q7RTX1 1/20 0.33
PPARG P37231 3/20 0.33
PPARD Q03181 3/20 0.33
PPARA Q07869 3/20 0.33
VDR P11473 1/20 0.33
TP53 P04637 1/20 0.32
GAA P10253 1/20 0.32
THRB P10828 1/20 0.32
ALDH1A1 P00352 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
CARM1 Q86X55 1/20 0.32
PRMT6 Q96LA8 1/20 0.32
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16681642 0.94 ELANE (0.35) TAS1R3TAS1R1PPARGPPARDPPARA
SCHEMBL13660382 0.94 ELANE (0.33) TAS1R3TAS1R1PPARGPPARDPPARA
SCHEMBL13191290 0.93 TAS1R3 (0.33) TAS1R3TAS1R1PPARGPPARDPPARA
SCHEMBL19139144 0.93 TAS1R3 (0.33) TAS1R3TAS1R1PPARGPPARDPPARA
SCHEMBL18202020 0.91 ELANE (0.36) TAS1R3TAS1R1VDRTP53GAA
SCHEMBL12678034 0.91 ALDH1A1 (0.35) PPARGPPARDPPARAALDH1A1L3MBTL1
SCHEMBL22267438 0.91 VDR (0.32) PPARGPPARDPPARAVDRTP53
SCHEMBL17130508 0.90 TAS1R3 (0.42) TAS1R3TAS1R1TP53GAATHRB
SCHEMBL15478870 0.90 MAPT (0.38) TAS1R3TAS1R1VDRTP53GAA
SCHEMBL13660286 0.90 VDR (0.32) PPARGPPARDPPARAVDRTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240027928-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE, AND IMAGE FORMING APPARATUS MITSUBISHI CHEMICAL CORPORATION (JP) 2024-01-25 US disclosed
US-9880477-B2 Electrophotographic photoreceptor and image forming apparatus MITSUBISHI CHEMICAL CORPORATION (JP) 2018-01-30 US disclosed
US-9665020-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2017-05-30 US disclosed
US-20160320717-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC CARTRIDGE, IMAGE FORMING APPARATUS, AND CHARGE TRANSPORT SUBSTANCE MITSUBISHI CHEMICAL CORPORATION (JP) 2016-11-03 US disclosed
US-20150355559-A1 CHARGE TRANSPORT SUBSTANCE, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE, AND IMAGE-FORMING APPARATUS MITSUBISHI CHEMICAL CORPORATION (JP) 2015-12-10 US disclosed
US-20140065532-A1 CHARGE TRANSPORT SUBSTANCE, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE, AND IMAGE-FORMING APPARATUS MITSUBISHI CHEMICAL CORPORATION (JP) 2014-03-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150355559-A1 CHARGE TRANSPORT SUBSTANCE, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE, AND IMAGE-FORMING APPARATUS PDE6C, SLC18A2, SLC1A2 TAS1R3 1028/4885TAS1R1 991/4885PPARG 3331/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.