SCHEMBL15499445

SCHEMBL15499445

CCCC(I)CCCC1CCC(COC2CCC(C)CC2)CC1

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16869869 0.88 MAPT (0.38) MAPT
SCHEMBL19226708 0.86 MAPT (0.43) MAPT
SCHEMBL19634168 0.84 MAPT (0.34) MAPT
SCHEMBL11251817 0.82 CYP1A2 (0.38) MAPT
SCHEMBL11264845 0.82 CYP1A2 (0.38) MAPT
SCHEMBL11251816 0.82 CYP1A2 (0.38) MAPT
SCHEMBL11264843 0.82 CYP1A2 (0.38) MAPT
SCHEMBL19634029 0.81 MAPT (0.34) MAPT
SCHEMBL11258619 0.80 CYP1A2 (0.37) MAPT
SCHEMBL11258621 0.80 CYP1A2 (0.37) MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170335195-A1 LIQUID-CRYSTAL MEDIUM MERCK PATENT GMBH (DE) 2017-11-23 — — US disclosed
US-20170335194-A1 LIQUID-CRYSTAL MEDIUM MERCK PATENT GMBH (DE) 2017-11-23 — — US disclosed
US-9737854-B2 Process for the purification of a liquid-crystal mixture MERCK PATENT GMBH (DE) 2017-08-22 — — US disclosed
US-9556382-B2 Polymerisable mixtures and the use thereof in liquid crystal displays MERCK PATENT GMBH (DE) 2017-01-31 — — US disclosed
US-9487702-B2 Liquid crystal medium MERCK PATENT GMBH (DE) 2016-11-08 — — US disclosed
US-20160272346-A1 FILLING DEVICE AND USE THEREOF FOR DISPENSING A FLUID MERCK PATENT GMBH (DE) 2016-09-22 — — US disclosed
US-9347002-B2 Liquid-crystalline medium MERCK PATENT GMBH (DE) 2016-05-24 — — US disclosed
US-20160060528-A1 COMPOUNDS AND LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2016-03-03 — — US disclosed
US-9181482-B2 Liquid-crystal display MERCK PATENT GMBH (DE) 2015-11-10 — — US disclosed
US-20150299574-A1 LIQUID CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2015-10-22 — — US disclosed
US-20150203758-A1 LIQUID-CRYSTALLINE MEDIA MERCK PATENT GMBH (DE) 2015-07-23 — — US disclosed
US-20150070609-A1 LIQUID CRYSTAL MEDIUM MERCK PATENT GMBH (DE) 2015-03-12 — — US disclosed
US-20150048276-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2015-02-19 — — US disclosed
US-8895117-B2 Polymerisable compounds and the use thereof in liquid-crystal media and liquid-crystal displays MERCK PATENT GMBH (DE) 2014-11-25 — — US disclosed
US-8871952-B2 Thiophene compounds for liquid-crystalline media MERCK PATENT GMBH (DE) 2014-10-28 — — US disclosed
US-20140070141-A1 THIOPHENE COMPOUNDS FOR LIQUID-CRYSTALLINE MEDIA MERCK PATENT GMBH (DE) 2014-03-13 — — US disclosed
US-20140061534-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2014-03-06 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160060528-A1 COMPOUNDS AND LIQUID-CRYSTALLINE MEDIUM MLX, XDH, CXCR1 MAPT 787/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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