Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16869869 | 0.92 | MAPT (0.38) | MAPTCYP1A2LMNAMAPK1HTT | |
| SCHEMBL18360728 | 0.84 | MAPT (0.32) | MAPT | |
| SCHEMBL15712130 | 0.81 | LMNA (0.34) | MAPTCYP1A2LMNAMAPK1HTT | |
| SCHEMBL15499445 | 0.81 | MAPT (0.32) | MAPT | |
| SCHEMBL4761965 | 0.79 | LMNA (0.42) | MAPTCYP1A2LMNAMAPK1HTT | |
| SCHEMBL16438983 | 0.77 | ALDH1A1 (0.32) | LMNA | |
| SCHEMBL16749934 | 0.77 | — | — | |
| SCHEMBL16809837 | 0.75 | — | — | |
| SCHEMBL19634168 | 0.75 | MAPT (0.34) | MAPTCYP1A2 | |
| SCHEMBL18538147 | 0.74 | MAPT (0.36) | MAPTCYP1A2LMNAMAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170335195-A1 | LIQUID-CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 2017-11-23 | — | — | US | disclosed |