SCHEMBL15501009

SCHEMBL15501009

Cc1cccc(N(c2cccc(C)c2)C2CCC(C3CCC(C)CC3)CC2)c1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 2/20 0.35
ACHE P22303 1/20 0.34
SLC6A2 P23975 2/20 0.33
CHRNA1 P02708 1/20 0.33
CHRNG P07510 1/20 0.33
CHRNB1 P11230 1/20 0.33
CHRNB2 P17787 1/20 0.33
CHRNB4 P30926 1/20 0.33
CHRNA3 P32297 1/20 0.33
CHRNA4 P43681 1/20 0.33
SLC6A3 Q01959 1/20 0.33
CHRND Q07001 1/20 0.33
HTR2C P28335 3/20 0.33
NISCH Q9Y2I1 1/20 0.33
CCR5 P51681 1/20 0.32
HTT P42858 1/20 0.32
MEN1 O00255 1/20 0.32
NPC1 O15118 1/20 0.32
NSD2 O96028 1/20 0.32
CASP3 P42574 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14037101 0.81 SLC6A2 (0.37) ACHESLC6A2CCR5HTR7SLC6A4
SCHEMBL20385000 0.75 SLC6A2 (0.40) ACHESLC6A2CCR5HTR7SLC6A4
SCHEMBL10109493 0.74 CCR5 (0.33) SLC6A2CCR5TDP1SLC6A4OPRM1
SCHEMBL13968327 0.73 TSHR (0.39) ACHESLC6A2CHRNA1CHRNGCHRNB1
SCHEMBL15501019 0.73 OPRM1 (0.38) SLC6A2SLC6A3CCR5POLBPTGIR
SCHEMBL24054526 0.72 ACHE (0.42) SIGMAR1ACHEHTR2CMEN1NPC1
SCHEMBL10109405 0.68 ESR2 (0.44) SLC6A2CCR5NPC1RAB9ASLC6A4
SCHEMBL10109594 0.68 MEN1 (0.37) SLC6A2CHRNA1CHRNGCHRNB1CHRNB2
SCHEMBL11692239 0.66 POLB (0.47) SIGMAR1ACHEHTR2CMEN1NPC1
SCHEMBL17704661 0.65 ACHE (0.38) ACHEHTTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1308494-B1 Organic electroluminescence element PIONEER CORP (JP) 2014-03-12 EP disclosed