Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.46 |
| ▸ | AGTR1 | P30556 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13826733 | 0.95 | LMNA (0.59) | LMNAALDH1A1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL15503158 | 0.85 | LMNA (0.49) | LMNAALDH1A1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL5527648 | 0.78 | ATM (0.51) | ALDH1A1HSP90AA1 | |
| SCHEMBL5527650 | 0.78 | ATM (0.51) | ALDH1A1HSP90AA1 | |
| SCHEMBL31192684 | 0.78 | ATM (0.51) | ALDH1A1HSP90AA1 | |
| SCHEMBL6743841 | 0.78 | HSP90AA1 (0.49) | LMNAALDH1A1KMT2AHSP90AA1AGTR1 | |
| SCHEMBL29010741 | 0.78 | ATM (0.59) | HSP90AA1 | |
| SCHEMBL13826734 | 0.78 | ATM (0.59) | HSP90AA1 | |
| SCHEMBL6743847 | 0.78 | HSP90AA1 (0.49) | LMNAALDH1A1KMT2AHSP90AA1AGTR1 | |
| SCHEMBL29378716 | 0.77 | NPC1 (0.63) | LMNAALDH1A1KMT2ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9302019-B2 | Fe(II) sequestering agents and uses thereof | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2016-04-05 | — | — | US | disclosed |
| US-20140072517-A1 | FE(II) SEQUESTERING AGENTS AND USES THEREOF | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW (US) | 2014-03-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140072517-A1 | FE(II) SEQUESTERING AGENTS AND USES THEREOF | SLC40A1, SLC39A14, SLC39A3 | LMNA 3224/4885ALDH1A1 3480/4885KMT2A 3618/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.