SCHEMBL15501786

SCHEMBL15501786

c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(-c4cccc5c4oc4ccccc45)cc3)n2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.56
MAPT P10636 9/20 0.47
ALDH1A1 P00352 4/20 0.46
KDM4E B2RXH2 3/20 0.46
POLB P06746 2/20 0.46
NPSR1 Q6W5P4 1/20 0.45
GGPS1 O95749 1/20 0.44
TSHR P16473 4/20 0.43
HPGD P15428 2/20 0.43
HSD17B10 Q99714 3/20 0.43
LMNA P02545 3/20 0.43
MAPK1 P28482 2/20 0.43
PRKDC P78527 3/20 0.42
PIK3CD O00329 2/20 0.42
PIK3CB P42338 2/20 0.42
TP53 P04637 1/20 0.42
NFKB1 P19838 1/20 0.42
NFKB2 Q00653 1/20 0.42
RELA Q04206 1/20 0.42
ATM Q13315 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15501851 1.00 ALOX5 (0.56) ALOX5MAPTALDH1A1KDM4EPOLB
SCHEMBL15501709 0.98 ALOX5 (0.55) ALOX5MAPTALDH1A1KDM4EPOLB
SCHEMBL22058584 0.98 ALOX5 (0.55) ALOX5MAPTALDH1A1KDM4EPOLB
SCHEMBL25645607 0.98 ALOX5 (0.55) ALOX5MAPTALDH1A1KDM4EPOLB
SCHEMBL25645603 0.98 ALOX5 (0.55) ALOX5MAPTALDH1A1KDM4EPOLB
SCHEMBL25645716 0.98 ALOX5 (0.55) ALOX5MAPTALDH1A1KDM4EPOLB
SCHEMBL25645965 0.97 ALOX5 (0.54) ALOX5MAPTALDH1A1KDM4EPOLB
SCHEMBL21563823 0.97 ALOX5 (0.54) ALOX5MAPTALDH1A1KDM4EPOLB
SCHEMBL15501852 0.97 ALOX5 (0.59) ALOX5MAPTALDH1A1KDM4EPOLB
SCHEMBL23027475 0.96 ALOX5 (0.52) ALOX5MAPTALDH1A1KDM4EPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230284470-A1 ORGANIC ELECTROLUMINESCENT DEVICE AND ORGANIC ELECTROLUMINESCENT COMPOUND DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2023-09-07 US disclosed
US-20230284470-A1 ORGANIC ELECTROLUMINESCENT DEVICE AND ORGANIC ELECTROLUMINESCENT COMPOUND DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2023-09-07 US disclosed
US-11659765-B2 Composition for organic optoelectronic element, organic optoelectronic element, and display device SAMSUNG SDI CO., LTD. (KR) 2023-05-23 US disclosed
US-11659765-B2 Composition for organic optoelectronic element, organic optoelectronic element, and display device SAMSUNG SDI CO., LTD. (KR) 2023-05-23 US disclosed
US-20220384744-A1 A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2022-12-01 US disclosed
US-RE49237-E1 Organic electroluminescence device and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2022-10-04 US disclosed
US-11374176-B2 Aromatic heterocyclic derivative, material for organic electroluminescent element, and organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2022-06-28 US disclosed
US-20220173322-A1 ORGANIC ELECTROLUMINESCENT COMPOUND, A PLURALITY OF HOST MATERIALS COMPRISING THE SAME, AND ORGANIC ELECTROLUMINESCENT DEVICE DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2022-06-02 US disclosed
US-20220059777-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2022-02-24 US disclosed
EP-3533794-B1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2022-02-23 EP disclosed
US-9397307-B2 Organic electroluminescence device and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2016-07-19 US disclosed
US-20160111655-A1 AROMATIC HETEROCYCLIC DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, AND ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2016-04-21 US disclosed
US-20160111655-A1 AROMATIC HETEROCYCLIC DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, AND ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2016-04-21 US disclosed
US-9209406-B2 Aromatic heterocyclic derivative, material for organic electroluminescent element, and organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2015-12-08 US disclosed
US-9209406-B2 Aromatic heterocyclic derivative, material for organic electroluminescent element, and organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2015-12-08 US disclosed
WO-2015165563-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2015-11-05 WO disclosed
US-20140231769-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2014-08-21 US disclosed
US-20140231769-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2014-08-21 US disclosed
US-20140073784-A1 AROMATIC HETEROCYCLIC DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT, AND ORGANIC ELECTROLUMINESCENCE ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2014-03-13 US disclosed
US-20140073784-A1 AROMATIC HETEROCYCLIC DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT, AND ORGANIC ELECTROLUMINESCENCE ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2014-03-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11374176-B2 Aromatic heterocyclic derivative, material for organic electroluminescent element, and organic electroluminescent element RER1, L1CAM, ESR1 ALOX5 3818/4885MAPT 3845/4885ALDH1A1 468/4885
US-20220384744-A1 A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME TELO2, PIEZO1, LIMS1 ALOX5 506/4885MAPT 2509/4885ALDH1A1 366/4885
US-20230284470-A1 ORGANIC ELECTROLUMINESCENT DEVICE AND ORGANIC ELECTROLUMINESCENT COMPOUND OR10J3, ICOSLG, L1CAM ALOX5 755/4885MAPT 1652/4885ALDH1A1 551/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.