Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 12/20 | 0.32 |
| ▸ | BCHE | P06276 | 8/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | GSK3A | P49840 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15509951 | 0.91 | KDM1A (0.32) | ACHEBCHEKDM1AMAOAMAOB | |
| SCHEMBL2533019 | 0.85 | POLB (0.35) | KDM1AMAOAMAOB | |
| SCHEMBL15509513 | 0.84 | ACHE (0.38) | ACHEBCHE | |
| SCHEMBL15509732 | 0.83 | KDM4E (0.32) | ACHEBCHE | |
| SCHEMBL15510306 | 0.83 | MTNR1A (0.36) | ACHEBCHE | |
| SCHEMBL15509415 | 0.82 | KMT2A (0.36) | ACHEBCHE | |
| SCHEMBL15509759 | 0.81 | PARP1 (0.38) | ACHEBCHE | |
| SCHEMBL2537520 | 0.81 | AR (0.40) | — | |
| SCHEMBL15509948 | 0.80 | ACHE (0.40) | ACHEBCHE | |
| SCHEMBL15509929 | 0.80 | ACHE (0.41) | ACHEBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2558449-B1 | NOVEL 3,3-DIMETHYL TETRAHYDROQUINOLINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2014-03-05 | — | — | EP | claimed |