Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 19/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 19/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2531406 | 0.87 | MTNR1A (0.35) | MTNR1AMTNR1B | |
| SCHEMBL15509951 | 0.83 | KDM1A (0.32) | BCHEACHE | |
| SCHEMBL15510019 | 0.83 | ACHE (0.32) | BCHEACHE | |
| SCHEMBL15510001 | 0.81 | ABL1 (0.41) | — | |
| SCHEMBL15509513 | 0.80 | ACHE (0.38) | BCHEACHE | |
| SCHEMBL15509948 | 0.80 | ACHE (0.40) | BCHEACHE | |
| SCHEMBL15509732 | 0.80 | KDM4E (0.32) | BCHEACHE | |
| SCHEMBL15510112 | 0.78 | ACHE (0.35) | BCHEACHE | |
| SCHEMBL15509415 | 0.78 | KMT2A (0.36) | BCHEACHE | |
| SCHEMBL15509929 | 0.78 | ACHE (0.41) | BCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2558449-B1 | NOVEL 3,3-DIMETHYL TETRAHYDROQUINOLINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2014-03-05 | — | — | EP | claimed |