Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.66 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.66 |
| ▸ | CYP4Z1 | Q86W10 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.44 |
| ▸ | CYP4F11 | Q9HBI6 | 1/20 | 0.44 |
| ▸ | CYP4F12 | Q9HCS2 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL68902 | 0.86 | CYP4F2 (0.85) | CYP4F2CYP4A11CYP4Z1TDP1EPHX2 | |
| SCHEMBL4506493 | 0.84 | CYP4F2 (0.66) | CYP4F2CYP4A11CYP4Z1TDP1HRH3 | |
| SCHEMBL24095167 | 0.83 | CYP4Z1 (0.50) | CYP4F2CYP4A11CYP4Z1LMNAMAPT | |
| SCHEMBL516523 | 0.83 | ADRB2 (0.48) | CYP4F2CYP4A11TDP1EPHX2HRH3 | |
| SCHEMBL879130 | 0.81 | CYP4F2 (0.77) | CYP4F2CYP4A11CYP4Z1TDP1EPHX2 | |
| SCHEMBL11437256 | 0.81 | CYP4F2 (0.77) | CYP4F2CYP4A11CYP4Z1TDP1EPHX2 | |
| SCHEMBL363982 | 0.81 | CYP4F2 (0.77) | CYP4F2CYP4A11CYP4Z1TDP1EPHX2 | |
| SCHEMBL10206072 | 0.81 | CYP4F2 (0.77) | CYP4F2CYP4A11CYP4Z1TDP1EPHX2 | |
| SCHEMBL457584 | 0.80 | ACACB (0.60) | CYP4F2CYP4A11FFAR1 | |
| SCHEMBL1587300 | 0.80 | CYP4F2 (0.74) | CYP4F2CYP4A11CYP4Z1TDP1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2313360-A1 | COMPOUNDS FOR THE TREATMENT OF METABOLIC DISEASES | Syddansk Universitet (DK) | 2011-04-27 | — | — | EP | disclosed |
| WO-2010012650-A1 | COMPOUNDS FOR THE TREATMENT OF METABOLIC DISEASES | SYDDANSK UNIVERSITET (DK) | 2010-02-04 | — | — | WO | disclosed |