SCHEMBL1551333

SCHEMBL1551333

C=CCNC(C)NCC(=O)O

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.35
ALDH1A1 P00352 2/20 0.35
LMNA P02545 1/20 0.35
PTGS2 P35354 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
ECE1 P42892 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.34
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
TSHR P16473 2/20 0.32
ABCC4 O15439 1/20 0.32
MME P08473 1/20 0.31
ACE P12821 1/20 0.31
CPA1 P15085 1/20 0.31
ACE2 Q9BYF1 1/20 0.31
FAAH O00519 1/20 0.31
KMT2A Q03164 1/20 0.31
HPGD P15428 1/20 0.30
HSD17B10 Q99714 1/20 0.30
SLC6A4 P31645 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL437245 0.98 MAPT (0.34) MAPTALDH1A1LMNAPTGS2TDP1
SCHEMBL3658182 0.92 MAPT (0.33) MAPTALDH1A1LMNAPTGS2TDP1
SCHEMBL8416121 0.80 SLC6A4 (0.38) ALDH1A1SMN1; SMN2NPC1RAB9ATSHR
SCHEMBL5570056 0.78 SLC6A4 (0.38) MAPTALDH1A1LMNAPTGS2TDP1
SCHEMBL3435876 0.77 MME (0.33) MAPTALDH1A1SMN1; SMN2TSHRABCC4
Sarcosine SCHEMBL27418475 0.74 ALDH1A1 (0.33) MAPTALDH1A1LMNAPTGS2TDP1
SCHEMBL23501484 0.74 ALDH1A1 (0.40) MAPTALDH1A1LMNAPTGS2TDP1
SCHEMBL22364723 0.73 MAPT (0.41) MAPTALDH1A1LMNAPTGS2TDP1
SCHEMBL29952635 0.72
SCHEMBL725364 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 230 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-11071202-A None JP disclosed
JP-4089406-A None JP disclosed
JP-63258802-A None JP disclosed
WO-2024123825-A1 NOOTKATONE FOR THE TREATMENT OF PSORIASIS OR ATOPIC DERMATITIS ENVEDA THERAPEUTICS, INC. (US) 2024-06-13 WO disclosed
WO-2024123830-A1 NOOTKATONE FOR THE TREATMENT OF GUT OR ABDOMINAL PAIN ENVEDA THERAPEUTICS, INC. (US) 2024-06-13 WO disclosed
WO-2024123828-A1 NOOTKATONE FOR THE TREATMENT OF DIABETIC DERMOPATHY OR DIABETIC PERIPHERAL NEUROPATHY ENVEDA THERAPEUTICS, INC. (US) 2024-06-13 WO disclosed
WO-2024123826-A1 NOOTKATONE FOR IMPROVING THE APPEARANCE OF SKIN ENVEDA THERAPEUTICS, INC. (US) 2024-06-13 WO disclosed
WO-2024123824-A1 NOOTKATONE FOR THE TREATMENT OF PRURITUS ENVEDA THERAPEUTICS, INC. (US) 2024-06-13 WO disclosed
CN-112771034-B Heteroaryl azole compound and pest control agent 日本曹达株式会社 2024-02-09 CN disclosed
CN-112930339-B (hetero) arylimidazole compound and pest control agent 日本曹达株式会社 2023-11-03 CN disclosed
US-5147445-A HERBICIDAL TRIAZOLE COMPOUNDS AND HERBICIDAL COMPOSITIONS CONTAINING THE SAME CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 1992-09-15 US disclosed
JP-H0489406-A DISEASE DAMAGE-PREVENTING AGENT FOR LAWN GRASS SUPPLY CONTROL:KK 1992-03-23 JP disclosed
EP-0408292-A2 Vinyl copolymer and adsorbent for microorganisms JAPAN VILENE COMPANY,LTD (JP) 1991-01-16 EP disclosed
EP-0332133-A1 Novel triazole compounds, process for producing the same, and herbicidal compositions containing the same Chugai Seiyaku Kabushiki Kaisha (JP) 1989-09-13 EP disclosed
JP-S63258802-A VIRAL INFECTION INHIBITOR FOR PUBLIC BATHHOUSE SANYO CHEM IND LTD 1988-10-26 JP disclosed
EP-0120480-B1 4H-3,1-BENZOXAZINE DERIVATIVES, PROCESS FOR PRODUCING THE SAME AND AGRICULTURAL OR HORTICULTURAL FUNGICIDE CONTAINING THE SAME Chugai Seiyaku Kabushiki Kaisha (JP) 1987-07-08 EP disclosed
US-4596801-A Applying fungicide to plants or soil CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 1986-06-24 US disclosed
US-4590198-A Fungicidal isonicotinanllide retals, their compositions and method of using them CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 1986-05-20 US disclosed
EP-0122410-A2 Fungicidal isonicotinanilide acetal derivatives, process for their production and fungicides containing them Chugai Seiyaku Kabushiki Kaisha (JP) 1984-10-24 EP disclosed
EP-0120480-A1 4H-3,1-benzoxazine derivatives, process for producing the same and agricultural or horticultural fungicide containing the same Chugai Seiyaku Kabushiki Kaisha (JP) 1984-10-03 EP disclosed