Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 known ✓ | P35354 | 1/20 | 0.34 |
| ▸ | ACE known ✓ | P12821 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ECE1 | P42892 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MME | P08473 | 1/20 | 0.30 |
| ▸ | CPA1 | P15085 | 1/20 | 0.30 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.30 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1551333 | 0.98 | MAPT (0.35) | MAPTALDH1A1LMNAPTGS2TDP1 | |
| SCHEMBL3658182 | 0.91 | MAPT (0.33) | MAPTALDH1A1LMNAPTGS2TDP1 | |
| SCHEMBL8416121 | 0.78 | SLC6A4 (0.38) | ALDH1A1SMN1; SMN2NPC1RAB9ATSHR | |
| SCHEMBL5570056 | 0.76 | SLC6A4 (0.38) | MAPTALDH1A1LMNAPTGS2TDP1 | |
| SCHEMBL3435876 | 0.76 | MME (0.33) | MAPTALDH1A1SMN1; SMN2ABCC4TSHR | |
| Sarcosine SCHEMBL27418475 | 0.73 | ALDH1A1 (0.33) | MAPTALDH1A1LMNAPTGS2TDP1 | |
| SCHEMBL23501484 | 0.73 | ALDH1A1 (0.40) | MAPTALDH1A1LMNAPTGS2TDP1 | |
| SCHEMBL22364723 | 0.72 | MAPT (0.41) | MAPTALDH1A1LMNAPTGS2TDP1 | |
| SCHEMBL725364 | 0.71 | — | — | |
| SCHEMBL253527 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 224 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2420141-B1 | Methods of reducing phytotoxicity of a pesticide | ORO AGRI INC (US) | 2016-10-12 | — | — | EP | claimed |
| WO-2012074486-A1 | MILK-BASED PESTICIDAL FORMULATION | ORO AGRI INTERNATIONAL LTD (KY) | 2012-06-07 | — | — | WO | claimed |
| EP-2420141-A1 | Methods of reducing phytotoxicity of a pesticide | Oro Agri, Inc (US) | 2012-02-22 | — | — | EP | claimed |
| US-20240116831-A1 | Methods and Compositions for Soil Regeneration and Improved Soil Hydrology | U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS COLLATERAL AGENT | 2024-04-11 | — | — | US | disclosed |
| WO-2023069313-A1 | METHODS AND COMPOSITIONS FOR SOIL REGENERATION AND IMPROVED SOIL HYDROLOGY | LOCUS SOLUTIONS IPCO, LLC (US) | 2023-04-27 | — | — | WO | disclosed |
| US-20210290690-A1 | COMPOSITIONS OF MORSELIZED UMBILICAL CORD AND/OR AMNIOTIC MEMBRANE AND METHODS OF USE THEREOF | U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION | 2021-09-23 | — | — | US | disclosed |
| US-11116800-B2 | Compositions of morselized umbilical cord and/or amniotic membrane and methods of use thereof | TISSUETECH, INC. (US) | 2021-09-14 | — | — | US | disclosed |
| US-20210276929-A1 | MICROBIAL SOIL ENHANCEMENT | LE KHANH (US) | 2021-09-09 | — | — | US | disclosed |
| US-20210230081-A1 | MICROBIAL SOLUTION | LE KHANH (US) | 2021-07-29 | — | — | US | disclosed |
| WO-2021132019-A1 | AGENT FOR IMPROVING CUTANEOUS RESIDENT FLORA BALANCE | 株式会社林原 | 2021-07-01 | — | — | WO | disclosed |
| US-10899676-B2 | Animal feed stock using microbial enhancement | Cisbay Global Inc. (US) | 2021-01-26 | — | — | US | disclosed |
| EP-0371564-A2 | (1H-azol-1-ylmethyl)substituted quinoline, quinazoline or quinoxaline derivatives | JANSSEN PHARMACEUTICA N.V. (BE) | 1990-06-06 | — | — | EP | disclosed |
| EP-0371559-A2 | Use of benzimidazoles in the treatment of epithelial disorders | JANSSEN PHARMACEUTICA N.V. (BE) | 1990-06-06 | — | — | EP | disclosed |
| EP-0344708-A2 | Composition for external application to skin | LION CORPORATION (JP) | 1989-12-06 | — | — | EP | disclosed |
| EP-0335442-A2 | Agents for preserving or restoring the soundness of the skin | JANSSEN PHARMACEUTICA N.V. (BE) | 1989-10-04 | — | — | EP | disclosed |
| EP-0332847-A2 | Composition for preventing graying of the hair and restoring grayed hair to its natural color | LION CORPORATION (JP) | 1989-09-20 | — | — | EP | disclosed |
| EP-0294808-A1 | Agent for external application and use thereof | LION CORPORATION (JP) | 1988-12-14 | — | — | EP | disclosed |
| EP-0293837-A2 | Composition for application to hair or scalp | Sugiyama, Keikichi (JP) | 1988-12-07 | — | — | EP | disclosed |
| EP-0260697-A2 | Composition for application to hair | LION CORPORATION (JP) | 1988-03-23 | — | — | EP | disclosed |
| EP-0256472-A2 | Cosmetic agent for application to skin | LION CORPORATION (JP) | 1988-02-24 | — | — | EP | disclosed |